Technology Process of Benzoic acid, 3-[(1-ethylpropyl)amino]-4-(2-oxo-1-pyrrolidinyl)-, methyl
ester
There total 6 articles about Benzoic acid, 3-[(1-ethylpropyl)amino]-4-(2-oxo-1-pyrrolidinyl)-, methyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide; sodium cyanoborohydride; triethylamine;
titanium tetrachloride;
In
ethanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 94 percent / H2SO4 / 18 h / Heating
2: 92 percent / NO2BF4 / CH2Cl2 / a) 10 deg C, 2 h, b) RT, 4 h
3: 95 percent / H2 / Pd/C / methanol / 1 h / 1551.44 Torr
4: 1.) Et3N, TiCl4, 2.) NaCNBH3 / 1.) CH2Cl2, RT, 18 h, 2.) CH2Cl2, 3 h
With
nitronium tetrafluoborate; sulfuric acid; hydrogen; titanium tetrachloride; sodium cyanoborohydride; triethylamine;
palladium on activated charcoal;
In
methanol; dichloromethane;
DOI:10.1021/jm980707k
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 66 percent / dimethylformamide / 24 h / Heating
2: 94 percent / H2SO4 / 18 h / Heating
3: 92 percent / NO2BF4 / CH2Cl2 / a) 10 deg C, 2 h, b) RT, 4 h
4: 95 percent / H2 / Pd/C / methanol / 1 h / 1551.44 Torr
5: 1.) Et3N, TiCl4, 2.) NaCNBH3 / 1.) CH2Cl2, RT, 18 h, 2.) CH2Cl2, 3 h
With
nitronium tetrafluoborate; sulfuric acid; hydrogen; titanium tetrachloride; sodium cyanoborohydride; triethylamine;
palladium on activated charcoal;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm980707k
