4,6-Diaminoisophthalaldehyde

Base Information

• Chemical Name: 4,6-Diaminoisophthalaldehyde
• CAS No.: 22146-36-7
• Molecular Formula: C8H8N2O2
• Molecular Weight: 164.16100
• Mol file: 22146-36-7.mol

Synonyms:4,6-Diamino-benzene-1,3-dicarbaldehyde;4,6-Diaminoisophthalaldehyde;4,6-diamino-isophthalaldehyde;4,6-Diamino-isophthalaldehyd;

Chemical Property of 4,6-Diaminoisophthalaldehyde

Chemical Property:

• PSA: 86.18000
• LogP: 1.63840

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6-Diaminoisophthalaldehyde

There total 6 articles about 4,6-Diaminoisophthalaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4,6-dinitro-1,3-benzenedicarboxaldehyde (65924-59-6) → 1,3-diamino-4,6-benzenedicarboxaldehyde (22146-36-7)

Guidance literature:

With hydrogenchloride; iron(II) sulfate; In ethanol; ammonia; water; at 80 ℃; for 1h;

Reference yield:

C24H24N6O6 (67640-41-9) → 1,3-diamino-4,6-benzenedicarboxaldehyde (22146-36-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 54 percent / aq. H₂SO₄ / toluene / 65 °C

2: 67 percent / ferrous sulfate heptahydrate; aq. ammonia / ethanol / 80 °C

With ammonium hydroxide; sulfuric acid; iron(II) sulfate; In ethanol; toluene;

DOI:10.1139/V06-094

Reference yield:

4,6-dinitro-m-xylene (616-72-8) → 1,3-diamino-4,6-benzenedicarboxaldehyde (22146-36-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 99 percent / I₂ / 16 h / 95 °C

2: 55 percent / aq. NaOH / ethanol / -5 - 5 °C

3: 54 percent / aq. H₂SO₄ / toluene / 65 °C

4: 67 percent / ferrous sulfate heptahydrate; aq. ammonia / ethanol / 80 °C

With ammonium hydroxide; sodium hydroxide; sulfuric acid; iodine; iron(II) sulfate; In ethanol; toluene;

DOI:10.1139/V06-094

upstream raw materials:

4,6-dinitro-1,3-benzenedicarboxaldehyde

C₂₄H₂₄N₆O₆

4,6-dinitro-m-xylene

m-xylene

Downstream raw materials:

2,8-diphenyl-pyrido[3,2-g]quinoline

4,5,6-triamino-isophthalaldehyde

acetic acid-(5-amino-2,4-diformyl-anilide)

Refernces

• 1、 Quast, Helmut,Schoen, Norbert. "Synthesis and Reactions of Some Pyridoquinolines (1,8-Diazaanthracenes)". . p. 133 - 146. Retrieved 2007/10/02.