4-(4-Nitrophenyl)-2-piperazinone

Base Information

• Chemical Name: 4-(4-Nitrophenyl)-2-piperazinone
• CAS No.: 223785-99-7
• Molecular Formula: C₁₀H₁₁N₃O₃
• Molecular Weight: 221.216
• Hs Code.: 2933599090
• Mol file: 223785-99-7.mol

Synonyms:

Chemical Property of 4-(4-Nitrophenyl)-2-piperazinone

Chemical Property:

• Boiling Point: 518.3±45.0 °C(Predicted)
• PKA: 14.77±0.20(Predicted)
• PSA: 81.65000
• Density: 1.332±0.06 g/cm3(Predicted)
• LogP: 1.39510

Purity/Quality:

99% ^*data from raw suppliers

4-(4-Nitrophenyl)-2-piperazinone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(4-Nitrophenyl)-2-piperazinone

There total 1 articles about 4-(4-Nitrophenyl)-2-piperazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

2-Ketopiperazine (5625-67-2) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → 4-(4-nitro-phenyl)-piperazin-2-one (223785-99-7)

Guidance literature:

upstream raw materials:

2-Ketopiperazine

4-Fluoronitrobenzene

Refernces

• 1、 -. "4-Aminothiazole derivatives, their preparation and their use as inhibitors of cyclin-dependent kinases". Example C(118). . Retrieved 2010/11/29.