8-Hydroxy Pitavastatin

Base Information

Chemical Name:8-Hydroxy Pitavastatin
CAS No.:224320-09-6
Molecular Formula:C₂₅H₂₄FNO₅
Molecular Weight:437.468
Hs Code.:
Mol file:224320-09-6.mol

Synonyms:

Suppliers and Price of 8-Hydroxy Pitavastatin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-HydroxyPitavastatin
10mg
$ 6325.00

TRC
8-HydroxyPitavastatin
50mg
$ 16225.00

TRC
8-HydroxyPitavastatin
25mg
$ 13475.00

Medical Isotopes, Inc.
8-HydroxyPitavastatin
10 mg
$ 6750.00

Total 3 raw suppliers

Chemical Property of 8-Hydroxy Pitavastatin

Chemical Property:

PSA：110.88000
LogP:4.22370

Purity/Quality:

≥90% ^*data from raw suppliers

8-HydroxyPitavastatin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 8-Hydroxy Pitavastatin is a metabolite of Pitavastatin, a competitive inhibitor of HMG-CoA reductase and is a known antilipemic agent.

Technology Process of 8-Hydroxy Pitavastatin

There total 2 articles about 8-Hydroxy Pitavastatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 147526-32-7
pitavastatin calcium salt

: 224320-09-6
8-Hydroxypitavastatin

Guidance literature:: With human hepatic microsomes; NADP; glucose 6-phosphate dehydrogenase; magnesium chloride; In water; at 37 ℃; for 2h; pH=7.4; Further Variations:; Reagents; reaction times; Enzyme kinetics; Product distribution;
DOI:10.1080/0049825021000017957

Reference yield:

: 4R,6S-(E)-6-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylethenyl]-4-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

: 224320-09-6
8-Hydroxypitavastatin

Guidance literature:: With recombinant microsomes expressing human CYP₂D₆; NADP; glucose 6-phosphate dehydrogenase; magnesium chloride; In water; at 37 ℃; for 0.5h; pH=7.4; Further Variations:; Reagents; reaction times; Product distribution;
DOI:10.1080/0049825021000017957