2-Propenoyl chloride, 3-(4-nitrophenyl)-

Base Information

• Chemical Name: 2-Propenoyl chloride, 3-(4-nitrophenyl)-
• CAS No.: 22440-58-0
• Molecular Formula: C₉H₆ClNO₃
• Molecular Weight: 211.605
• Mol file: 22440-58-0.mol

Synonyms:3-(4-nitrophenyl)-2-propenoyl chloride;4-nitrocinnamic acid chloride;(E)-4-nitrocinnamic acid chloride;p-nitrocinnamic acid chloride;trans-4-nitrocinnamoyl chloride;4'-nitrocinnamoyl chloride;

Chemical Property of 2-Propenoyl chloride, 3-(4-nitrophenyl)-

Chemical Property:

• PSA: 62.89000
• LogP: 2.89660

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propenoyl chloride, 3-(4-nitrophenyl)-

There total 8 articles about 2-Propenoyl chloride, 3-(4-nitrophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-nitro-trans-cinnamic acid (882-06-4) → (E)-4-nitrocinnamic acid chloride (22440-58-0,61921-33-3)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2009.08.047

Reference yield: 96.0%

p-nitrocinnamic acid (619-89-6) → p-nitrocinnamoyl chloride (61921-33-3,22440-58-0)

Guidance literature:

With phosgene; In water; at 20 ℃; for 4h;

DOI:10.1016/j.ejmech.2019.02.074

Reference yield:

4-nitrobenzaldehdye (555-16-8) → p-nitrocinnamoyl chloride (61921-33-3,22440-58-0)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine; pyridine / Heating

2: SOCl₂ / 2 h / Heating

With piperidine; pyridine; thionyl chloride; 1: Condensation / 2: Substitution;

DOI:10.1016/S0014-827X(00)00063-X

upstream raw materials:

p-nitrocinnamic acid

4-nitrobenzaldehdye

4-nitro-trans-cinnamic acid

Downstream raw materials:

1-(p-nitrophenyl)-3-bromopropene-1

p-Nitro-cinnamyl-p-tolyl-ether

4-Methyl-2-<1-(p-nitrophenyl)-1-propenyl>-phenol

4-nitro-trans-cinnamic acid-(4-dimethylamino-anilide)