1-(3-METHYLPHENYL)-2-NITROETHENE

Base Information

• Chemical Name: 1-(3-METHYLPHENYL)-2-NITROETHENE
• CAS No.: 22568-43-0
• Molecular Formula: C9H9NO2
• Molecular Weight: 163.176
• Hs Code.: 2904209090
• Mol file: 22568-43-0.mol

Synonyms:2-Nitro-1-m-tolyl-aethylen;

Chemical Property of 1-(3-METHYLPHENYL)-2-NITROETHENE

Chemical Property:

• Vapor Pressure: 0.01mmHg at 25°C
• Boiling Point: 272.814oC at 760 mmHg
• Flash Point: 123.244oC
• PSA: 45.82000
• Density: 1.141g/cm3
• LogP: 2.76560

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3-METHYLPHENYL)-2-NITROETHENE

There total 10 articles about 1-(3-METHYLPHENYL)-2-NITROETHENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

nitromethane (75-52-5) + m-tolyl aldehyde (620-23-5) → (E)-1-methyl-3-(2-nitrovinyl)benzene (22568-43-0)

Guidance literature:

With sodium hydroxide; In ethanol; at 0 ℃; for 2h;

Reference yield: 95.0%

nitromethane (75-52-5) + m-tolyl aldehyde (620-23-5) → 1-methyl-3-(2-nitrovinyl)benzene (22568-43-0,62248-93-5)

Guidance literature:

nitromethane; m-tolyl aldehyde; With sodium hydroxide; In ethanol; water; at 0 ℃; for 2h;

With hydrogenchloride; In water; Cooling with ice;

Reference yield: 94.0%

→ (E)-1-methyl-3-(2-nitrovinyl)benzene (22568-43-0)

Guidance literature:

upstream raw materials:

nitromethane

m-tolyl aldehyde

3-methylstyrene

3-(3-methylphenyl)prop-2-en-1-al

Downstream raw materials:

ethyl (1R,2R,3S,4R)-1-acetyl-4-hydroxy-4-methyl-3-nitro-2-m-tolyl-cyclohexanecarboxylate

(R)-2-(2-nitro-1-m-tolylethyl)-4,7-dihydro-1H-indole

(R)-2,2-dimethyl-4-nitro-3-(3-tolyl)butanal

(R)--3-chloro-3-((S)-2-nitro-1-(m-tolyl)ethyl)indolin-2-one

Refernces

• 1、 Ni, Qijian,Wang, Xuyang,Zeng, Da,Wu, Qianling,Song, Xiaoxiao. "Organocatalytic Asymmetric Synthesis of Aza-Spirooxindoles via Michael/Friedel-Crafts Cascade Reaction of 1,3-Nitroenynes and 3-Pyrrolyloxindoles". supporting information. p. 2273 - 2278. Retrieved 2021/04/05.
• 2、 Min, Sun-Joon,Park, Sangwoon,Yoon, Seungri. "Metal-free Synthesis of β-Nitrostyrenes via DDQ-Catalyzed Nitration". . p. 525 - 528. Retrieved 2021/02/22.