1-{3-Fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone

Base Information

Chemical Name:1-{3-Fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone
CAS No.:5932-94-5
Molecular Formula:C₈H₁₅NO
Molecular Weight:141.213
Hs Code.:
DSSTox Substance ID:DTXSID90359897
Wikidata:Q82141319
ChEMBL ID:CHEMBL1462622

Synonyms:5932-94-5;ST051107;CBMicro_038207;Oprea1_513649;MLS000681340;CHEMBL1462622;DTXSID90359897;HMS2730G09;STK764435;AKOS001625266;SMR000267725;BIM-0038085.P001;SR-01000451953;SR-01000451953-1;1-{3-fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone;1-{3-fluoro-4-[4-(4-fluorobenzoyl)piperazin-1-yl]phenyl}propan-1-one;1-(3-fluoro-4-{4-[(4-fluorophenyl)carbonyl]piperazin-1-yl}phenyl)propan-1-one

Suppliers and Price of 1-{3-Fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Chemical Property of 1-{3-Fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone

Chemical Property:

Vapor Pressure:8.99E-12mmHg at 25°C
Boiling Point:541.1°C at 760 mmHg
Flash Point:281°C
Density:1.252g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:358.14928421
Heavy Atom Count:26
Complexity:500

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)C1=CC(=C(C=C1)N2CCN(CC2)C(=O)C3=CC=C(C=C3)F)F

Technology Process of 1-{3-Fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone

There total 4 articles about 1-{3-Fluoro-4-[4-(4-fluorobenzoyl)-1-piperazinyl]phenyl}-1-propanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5993-02-2
2-(1,1-dimethyl-but-2-ynylamino)-ethanol

: 5932-94-5
5,5,7-Trimethyl-2,3,4,5-tetrahydro-1,4-oxazepin

Guidance literature:: With potassium hydroxide; In xylene; for 4h; Heating;
DOI:10.1021/jo01339a026

Reference yield:

: 31914-32-6
1,1-dimethyl-2-butynylamine

: 5932-94-5
5,5,7-Trimethyl-2,3,4,5-tetrahydro-1,4-oxazepin

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 16 h / 60 °C

2: KOH / xylene / 4 h / Heating

With potassium hydroxide; In methanol; xylene;
DOI:10.1021/jo01339a026

Reference yield:

: 2978-58-7
1,1-dimethylprop-3-ynylamine

: 5932-94-5
5,5,7-Trimethyl-2,3,4,5-tetrahydro-1,4-oxazepin

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaNH₂, liq. NH₃, Et₂O, (ii) /BRN= 969135/

2: methanol / 16 h / 60 °C

3: KOH / xylene / 4 h / Heating

With potassium hydroxide; In methanol; xylene;
DOI:10.1021/jo01339a026