(4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Base Information

Chemical Name:(4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone
CAS No.:226703-78-2
Molecular Formula:C17H21NO4
Molecular Weight:303.358
Hs Code.:
DSSTox Substance ID:DTXSID301120345
Nikkaji Number:J2.471.465I
Mol file:226703-78-2.mol

Synonyms:226703-78-2;(4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone;(4S)-4-benzyl-3-[(2S,3S)-3-hydroxy-2,4-dimethylpent-4-enoyl]-1,3-oxazolidin-2-one;NZNQVFXLNMUYFI-AEGPPILISA-N;DTXSID301120345;(4S)-3-[(2S,3S)-2,4-Dimethyl-3-hydroxy-4-pentenoyl]-4beta-benzyloxazolidine-2-one

Suppliers and Price of (4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone
5mg
$ 120.00

TRC
(4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone
100mg
$ 1305.00

Medical Isotopes, Inc.
(4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone
25 mg
$ 940.00

Total 1 raw suppliers

Chemical Property of (4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

Chemical Property:

PSA：66.84000
LogP:2.08750
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:303.14705815
Heavy Atom Count:22
Complexity:442

Purity/Quality:: (4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(C(=C)C)O)C(=O)N1C(COC1=O)CC2=CC=CC=C2
Isomeric SMILES:C[C@@H]([C@@H](C(=C)C)O)C(=O)N1[C@H](COC1=O)CC2=CC=CC=C2
Uses (4S)-3-[(2S,3S)-3-hydroxy-2,4-dimethyl-1-oxo-4-pentenyl]-4-(phenylmethyl)-2-oxazolidinone is an intermediate in the synthesis of substituents used in the preparation of Jasplakinolide (J210700), is an potent inhibitor of prostrate and breast carcinoma cell proliferation.

Technology Process of (4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone

There total 1 articles about (4S)-3-[(2S,3S)-3-Hydroxy-2,4-dimethyl-1-oxo-4-penten-1-yl]-4-(phenylmethyl)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 78-85-3,25120-30-3
2-methylpropenal

: 131685-53-5,101711-78-8
(S)-4-benzyl-3-propionyl-2-oxazolidinone

: 226703-78-2
C₁₇H₂₁NO₄

Guidance literature:: (S)-4-benzyl-3-propionyl-2-oxazolidinone; With di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 0.833333h;

2-methylpropenal; In dichloromethane; at -78 - 0 ℃; for 1.66667h; pH=7;

With dihydrogen peroxide; In methanol; dichloromethane; at 0 ℃; for 1h; pH=7; Further stages.;
DOI:10.1021/ol070855h