Cyclohexanamine, 2-(4-methoxyphenyl)-

Base Information

Chemical Name:Cyclohexanamine, 2-(4-methoxyphenyl)-
CAS No.:22720-25-8
Molecular Formula:C₁₃H₁₉NO
Molecular Weight:205.3
Hs Code.:
DSSTox Substance ID:DTXSID20483154
Mol file:22720-25-8.mol

Synonyms:22720-25-8;2-(4-Methoxyphenyl)cyclohexanamine;Cyclohexanamine, 2-(4-methoxyphenyl)-;SCHEMBL4257203;DTXSID20483154;AKOS011896337

Suppliers and Price of Cyclohexanamine, 2-(4-methoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Cyclohexanamine, 2-(4-methoxyphenyl)-

Chemical Property:

PSA：35.25000
LogP:3.38040
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:205.146664230
Heavy Atom Count:15
Complexity:187

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2CCCCC2N

Technology Process of Cyclohexanamine, 2-(4-methoxyphenyl)-

There total 5 articles about Cyclohexanamine, 2-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-((1S,2S)-2-Azido-cyclohexyl)-4-methoxy-benzene

: 22720-25-8,53365-43-8,53365-44-9,121916-02-7,121916-05-0
(1S,2S)-2-(4-Methoxy-phenyl)-cyclohexylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 2585.7 Torr;
DOI:10.1021/jm950833d

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 22720-25-8,53365-43-8,53365-44-9,121916-02-7,121916-05-0
(1S,2S)-2-(4-Methoxy-phenyl)-cyclohexylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) t-BuLi, 2.) BF₃*Et₂O / 1.) n-pentane, THF, -78 deg C, 30 min, 2.) n-pentane, THF, , -78 deg C, 15 min

2: diethyl azodicarboxylate, Ph₃P, diphenylphosphorazidate / tetrahydrofuran / -78 - 20 °C

3: H₂ / 10percent Pd/C / ethanol / 2585.7 Torr

With diphenyl phosphoryl azide; boron trifluoride diethyl etherate; hydrogen; tert.-butyl lithium; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm950833d

Reference yield:

: 20859-19-2,20859-20-5,89008-80-0,146744-35-6
(+/-)-trans-2-(4-methoxyphenyl)cyclohexanol

: 22720-25-8,53365-43-8,53365-44-9,121916-02-7,121916-05-0
(1S,2S)-2-(4-Methoxy-phenyl)-cyclohexylamine

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl azodicarboxylate, Ph₃P, diphenylphosphorazidate / tetrahydrofuran / -78 - 20 °C

2: H₂ / 10percent Pd/C / ethanol / 2585.7 Torr

With diphenyl phosphoryl azide; hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm950833d