1-(Diphenylphosphanyl)piperidine

Base Information

• Chemical Name: 1-(Diphenylphosphanyl)piperidine
• CAS No.: 22859-54-7
• Molecular Formula: C17H20NP
• Molecular Weight: 269.326
• DSSTox Substance ID: DTXSID30503579
• Nikkaji Number: J1.643.645C
• Wikidata: Q82357518
• Mol file: 22859-54-7.mol

Synonyms:1-(Diphenylphosphanyl)piperidine;22859-54-7;diphenylpiperidino-phosphine;SCHEMBL20091630;DTXSID30503579

Chemical Property of 1-(Diphenylphosphanyl)piperidine

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 269.133336640
• Heavy Atom Count: 19
• Complexity: 232

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(CC1)P(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 1-(Diphenylphosphanyl)piperidine

There total 3 articles about 1-(Diphenylphosphanyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

piperidine (110-89-4) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → 1-(diphenylphosphino)piperidine (22859-54-7)

Guidance literature:

In benzene; 1.) 5-10 deg C, 2.) room temp., 12 h;

DOI:10.1055/s-1980-29117

Reference yield:

Diphenyl-thiophosphinsaere-piperidid (35259-94-0) → 1-(diphenylphosphino)piperidine (22859-54-7)

Guidance literature:

With triethyloxonium fluoroborate; tetra-n-butylammonium cyanide; Multistep reaction; 1.) CH₂Cl₂, 2.) CH₂Cl₂;

Reference yield:

→ 1-(diphenylphosphino)piperidine (22859-54-7)

Guidance literature:

aus Diphenyl-chlorphosphin in Bzl. durch Eintropfen in eine benzol. Piperidin-Lsg. <0-5grad; 1/2 Std.>;

DOI:10.1021/jo01061a617

upstream raw materials:

piperidine

chloro-diphenylphosphine

Diphenyl-thiophosphinsaere-piperidid

Downstream raw materials:

Triphenyl-piperidin-1-yl-phosphonium; bromide

[Ru((CH₃)5C₅)(CH₃CN)2((C₆H₅)2PN(C₅H₁₀))]⁽¹⁺⁾*PF₆^(1-)=[Ru((CH₃)5C₅)(CH₃CN)2((C₆H₅)2PN(C₅H₁₀))][PF₆]

[Ru(C₅H₅)(CH₃CN)2((C₆H₅)2PN(C₅H₁₀))]⁽¹⁺⁾*PF₆^(1-)=[Ru(C₅H₅)(CH₃CN)2((C₆H₅)2PN(C₅H₁₀))][PF₆]