2,2-Dimethyl-1,3-dioxole

Base Information

• Chemical Name: 2,2-Dimethyl-1,3-dioxole
• CAS No.: 22945-10-4
• Molecular Formula: C5H8O2
• Molecular Weight: 100.117
• DSSTox Substance ID: DTXSID00432145
• Nikkaji Number: J408.189G
• Wikidata: Q82246205
• Mol file: 22945-10-4.mol

Synonyms:2,2-dimethyl-1,3-dioxole;22945-10-4;1,3-Dioxole, 2,2-dimethyl-;SCHEMBL787575;2,2-dimethyl-1,3-dioxolene;DTXSID00432145

Chemical Property of 2,2-Dimethyl-1,3-dioxole

Chemical Property:

• PSA: 18.46000
• LogP: 1.24050
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 100.052429494
• Heavy Atom Count: 7
• Complexity: 84.3

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1(OC=CO1)C

Technology Process of 2,2-Dimethyl-1,3-dioxole

There total 1 articles about 2,2-Dimethyl-1,3-dioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

C19H18O2 (82140-93-0,130942-05-1) → 2,2-dimethyl-[1,3]dioxole (22945-10-4) + anthracene (120-12-7)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; at 600 ℃; for 1.5h;

DOI:10.1021/jo048037f

Reference yield: 96.0%

2,2-dimethyl-[1,3]dioxole (22945-10-4) + C13H9BrO4 → C18H17BrO6

Guidance literature:

C₁₃H₉BrO₄; With (1R,3'r)-3,3'-bis(perfluorophenyl)[1,1'-binaphthalene]-2,2'-diol; N-ethyl-N,N-diisopropylamine; ytterbium(III) triflate; In dichloromethane; at 0 ℃; for 0.166667h; Molecular sieve; Inert atmosphere;

2,2-dimethyl-[1,3]dioxole; In dichloromethane; at 0 - 20 ℃; for 10h; enantioselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1002/anie.201908284

Reference yield: 95.0%

2,2-dimethyl-[1,3]dioxole (22945-10-4) + C14H12O4 → C19H20O6

Guidance literature:

C₁₄H₁₂O₄; With (1R,3'r)-3,3'-bis(perfluorophenyl)[1,1'-binaphthalene]-2,2'-diol; N-ethyl-N,N-diisopropylamine; ytterbium(III) triflate; In dichloromethane; at 0 ℃; for 0.166667h; Molecular sieve; Inert atmosphere;

2,2-dimethyl-[1,3]dioxole; In dichloromethane; at 0 - 20 ℃; for 18h; enantioselective reaction; Molecular sieve; Inert atmosphere;

DOI:10.1002/anie.201908284

upstream raw materials:

C₁₉H₁₈O₂

Downstream raw materials:

3,3-dimethyl-6-(toluene-4-sulfonyl)-2,4-dioxa-6-aza-bicyclo[3.2.0]heptan-7-one

(1R,2S,6S,7R)-4,4-Dimethyl-1-(toluene-4-sulfonyl)-3,5,8-trioxa-tricyclo[5.2.2.0^2,6]undec-10-en-9-one

(1R,2R,6R,7R)-4,4-Dimethyl-1-(toluene-4-sulfonyl)-3,5,8-trioxa-tricyclo[5.2.2.0^2,6]undec-10-en-9-one

3,3-Dimethyl-7-phenyl-2,4,6-trioxa-bicyclo[3.2.0]heptane-7-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester