Diphenyl[2-(trifluoromethyl)phenyl]phosphane

Base Information

• Chemical Name: Diphenyl[2-(trifluoromethyl)phenyl]phosphane
• CAS No.: 25688-44-2
• Molecular Formula: C19H14 F3 P
• Molecular Weight: 330.289
• NSC Number: 193780
• DSSTox Substance ID: DTXSID50307677
• Nikkaji Number: J1.479.468I
• Wikidata: Q82055179
• Mol file: 25688-44-2.mol

Synonyms:diphenyl[2-(trifluoromethyl)phenyl]phosphane;25688-44-2;NSC193780;o-trifluoromethylphenyldiphenylphosphine;SCHEMBL10792614;DTXSID50307677;AKOS024262952;NSC-193780

Chemical Property of Diphenyl[2-(trifluoromethyl)phenyl]phosphane

Chemical Property:

• Vapor Pressure: 1.61E-05mmHg at 25°C
• Boiling Point: 376.1°C at 760 mmHg
• Flash Point: 181.3°C
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 330.07852193
• Heavy Atom Count: 23
• Complexity: 338

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3C(F)(F)F

Technology Process of Diphenyl[2-(trifluoromethyl)phenyl]phosphane

There total 6 articles about Diphenyl[2-(trifluoromethyl)phenyl]phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-fluoro-2-trifluoromethylbenzene (392-85-8) + magnesium chloride diphenylphosphanide → [2-(trifluoromethyl)phenyl]diphenylphosphine (25688-44-2)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

DOI:10.1016/j.jorganchem.2006.01.001

Reference yield: 70.0%

o-trifluoromethylphenyl bromide (392-83-6) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → [2-(trifluoromethyl)phenyl]diphenylphosphine (25688-44-2)

Guidance literature:

o-trifluoromethylphenyl bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h; Inert atmosphere;

chloro-diphenylphosphine; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h; Inert atmosphere;

Reference yield: 63.0%

o-trifluoromethylphenyl bromide (392-83-6) + magnesium chloride diphenylphosphanide → [2-(trifluoromethyl)phenyl]diphenylphosphine (25688-44-2)

Guidance literature:

(2,2'-bipyridine)nickel(II) dibromide; In N,N-dimethyl-formamide; at 110 ℃; for 0.25h;

DOI:10.1016/j.jorganchem.2006.01.001

upstream raw materials:

o-trifluoromethylphenyl bromide

chloro-diphenylphosphine

1-fluoro-2-trifluoromethylbenzene

2-(trifluoromethyl)phenyllithium

Downstream raw materials:

trans-[RhCl(CO)(PPh₂(2-C₆H₄CF₃))2]