2-(4-(Thien-2-yl)phenyl)thiophene

Base Information

• Chemical Name: 2-(4-(Thien-2-yl)phenyl)thiophene
• CAS No.: 23354-94-1
• Molecular Formula: C14H10S2
• Molecular Weight: 242.365
• DSSTox Substance ID: DTXSID90456678
• Nikkaji Number: J876.160D
• Wikidata: Q82279232
• Mol file: 23354-94-1.mol

Synonyms:2-(4-(Thien-2-yl)phenyl)thiophene;23354-94-1;2-(4-thiophen-2-ylphenyl)thiophene;1,4-Di(2-thienyl)benzene;Thiophene, 2,2'-(1,4-phenylene)bis-;1,4-bis(2-thienyl)benzene;1,4-di-(2-thienyl)benzene;SCHEMBL338810;DTXSID90456678;MFCD11224849;AKOS024389346;AS-6243;CS-0163214;2-[4-(THIOPHEN-2-YL)PHENYL]THIOPHENE;D80694

Chemical Property of 2-(4-(Thien-2-yl)phenyl)thiophene

Chemical Property:

• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 242.02239267
• Heavy Atom Count: 16
• Complexity: 197

Purity/Quality:

≥99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CSC(=C1)C2=CC=C(C=C2)C3=CC=CS3

Technology Process of 2-(4-(Thien-2-yl)phenyl)thiophene

There total 20 articles about 2-(4-(Thien-2-yl)phenyl)thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

thiophene boronic acid (6165-68-0) + 1.4-dibromobenzene (106-37-6) → 1,4-bis(2-thienyl)benzene (23354-94-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 2-ethoxy-ethanol; water; at 130 ℃; for 0.25h;

DOI:10.1002/ejoc.201200076

Reference yield: 91.0%

bromochlorobenzene (106-39-8) + 2-(trimethylstannyl)thiophene (37496-13-2) → 1,4-bis(2-thienyl)benzene (23354-94-1) + 2-(4-chlorophenyl)thiophene (40133-23-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 120 ℃; for 24h; Reagent/catalyst; Solvent; Temperature; Sealed tube;

DOI:10.1039/c5tc01013f

Reference yield: 91.0%

1,4-phenylenebis[1-((ethoxycarbonothioyl)thio)-4-oxobutan-4,1-diyl] bis(2,2-dimethylpropanoate) (1509927-91-6) → 1,4-bis(2-thienyl)benzene (23354-94-1)

Guidance literature:

With acetic acid; potassium iodide; at 110 ℃; for 0.0833333h; Microwave irradiation;

DOI:10.1021/ol403310f

upstream raw materials:

thiophene boronic acid

1.4-dibromobenzene

2-thienylzinc chloride

para-diiodobenzene

Downstream raw materials:

1,4-bis-(5-bromothiophen-2-yl)benzene

1,4-bis(3,5-dibromo-2-thienyl)benzene

1,4-bis(3-bromothiophen-2-yl)benzene

1,4-bis(3-butylthio-2-thienyl)benzene