(S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Base Information

Chemical Name:(S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
CAS No.:23844-21-5
Molecular Formula:C12H14N2
Molecular Weight:186.257
Hs Code.:
DSSTox Substance ID:DTXSID70351617
Nikkaji Number:J1.249.301K
Wikidata:Q82128166
Mol file:23844-21-5.mol

Synonyms:23844-21-5;(S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole;(1~{S})-1-methyl-2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole;(S)-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole;SCHEMBL21012020;DTXSID70351617;(1S)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole;(-)-1,2,3,4-Tetrahydroharman;(1s)-1-methyl-2,3,4,9-tetrahydro-1h-b-carboline;(R,S)-1-Methyl-2,3,4,9-tetrahydro-1H-I(2)-carboline

Suppliers and Price of (S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
(S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
1g
$ 984.90

AccelPharmtech
(1S)-2,3,4,9-tetrahydro-1-methyl-1H-Pyrido[3,4-b]indole 97.00%
25G
$ 4010.00

AccelPharmtech
(1S)-2,3,4,9-tetrahydro-1-methyl-1H-Pyrido[3,4-b]indole 97.00%
5G
$ 2180.00

AccelPharmtech
(1S)-2,3,4,9-tetrahydro-1-methyl-1H-Pyrido[3,4-b]indole 97.00%
1G
$ 1940.00

Total 3 raw suppliers

Chemical Property of (S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Chemical Property:

PSA：27.82000
LogP:2.70340
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:186.115698455
Heavy Atom Count:14
Complexity:216

Purity/Quality:

99% ^*data from raw suppliers

(S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C2=C(CCN1)C3=CC=CC=C3N2
Isomeric SMILES:C[C@H]1C2=C(CCN1)C3=CC=CC=C3N2

Technology Process of (S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

There total 31 articles about (S)-1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 525-41-7
1-methyl-4,9-dihydro-3H-β-carboline

: 525-40-6,2506-10-7,23844-21-5,2254-36-6
(R)-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole

Guidance literature:: With formic acid; (S,S)-TsDPEN-Ru(II); triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h; optical yield given as %ee; enantioselective reaction;
DOI:10.1021/ol9011772

Reference yield: 93.0%

: 2506-10-7
eleagnine

: 525-40-6,2506-10-7,23844-21-5,2254-36-6
(R)-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole

Guidance literature:: With hydrogenchloride; borane-ammonia complex; In aq. phosphate buffer; N,N-dimethyl-formamide; at 37 ℃; for 24h; pH=7.8;
DOI:10.1021/ja4051235

Reference yield: 85.0%

: C₁₆H₁₈N₂O₂

: 525-40-6,2506-10-7,23844-21-5,2254-36-6
(R)-1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; formic acid; triphenylphosphine; In tetrahydrofuran; at 40 ℃; for 2h; Reagent/catalyst;
DOI:10.1016/j.tetasy.2017.10.019