3-Ethoxycarbonyl-4-(4-iodophenyl)pyrrole

Base Information

Chemical Name:3-Ethoxycarbonyl-4-(4-iodophenyl)pyrrole
CAS No.:238760-82-2
Molecular Formula:C13H12INO2
Molecular Weight:341.148
Hs Code.:
DSSTox Substance ID:DTXSID30458530
Nikkaji Number:J1.103.182J
Wikidata:Q82281900
Mol file:238760-82-2.mol

Synonyms:3-ethoxycarbonyl-4-(4-iodophenyl)pyrrole;238760-82-2;SCHEMBL6976375;DTXSID30458530;HJCGBYQPFRAOIX-UHFFFAOYSA-N;4-(4-Iodophenyl)-1H-pyrrole-3-carboxylic acid ethyl ester

Suppliers and Price of 3-Ethoxycarbonyl-4-(4-iodophenyl)pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Ethoxycarbonyl-4-(4-iodophenyl)pyrrole

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:340.99128
Heavy Atom Count:17
Complexity:264

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CNC=C1C2=CC=C(C=C2)I

Technology Process of 3-Ethoxycarbonyl-4-(4-iodophenyl)pyrrole

There total 2 articles about 3-Ethoxycarbonyl-4-(4-iodophenyl)pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 34633-08-4
(E)-ethyl 3-(4-iodophenyl)prop-2-enoate

: 238760-82-2
3-ethoxycarbonyl-4-(4-iodophenyl)pyrrole

Guidance literature:: With sodium hydride; In diethyl ether; dimethyl sulfoxide; at 20 ℃; for 1h;
DOI:10.1016/S0040-4020(99)00339-7

Reference yield:

: 15164-44-0
p-(iodophenyl)carboxaldehyde

: 238760-82-2
3-ethoxycarbonyl-4-(4-iodophenyl)pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / piperidine / pyridine / 7 h / Heating

2: 65 percent / NaH / diethyl ether; dimethylsulfoxide / 1 h / 20 °C

With piperidine; sodium hydride; In pyridine; diethyl ether; dimethyl sulfoxide; 1: Condensation / 2: Cyclization;
DOI:10.1016/S0040-4020(99)00339-7