Ethyl 2-chloro-3-oxopentanoate

Base Information

• Chemical Name: Ethyl 2-chloro-3-oxopentanoate
• CAS No.: 24045-73-6
• Molecular Formula: C7H11ClO3
• Molecular Weight: 178.616
• European Community (EC) Number: 886-096-2
• DSSTox Substance ID: DTXSID90513073
• Nikkaji Number: J2.142.282G
• Mol file: 24045-73-6.mol

Synonyms:ethyl 2-chloro-3-oxopentanoate;24045-73-6;Pentanoic acid, 2-chloro-3-oxo-, ethyl ester;ethyl2-chloro-3-oxopentanoate;SCHEMBL1597955;DTXSID90513073;GEMFOQNVIPGLNR-UHFFFAOYSA-N;AMY32491;AKOS026726419;2-Chloro-3-oxo-pentanoic acid ethyl ester;D87881;EN300-107183

Chemical Property of Ethyl 2-chloro-3-oxopentanoate

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 178.0396719
• Heavy Atom Count: 11
• Complexity: 156

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)C(C(=O)OCC)Cl

Technology Process of Ethyl 2-chloro-3-oxopentanoate

There total 1 articles about Ethyl 2-chloro-3-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ ethyl 4-ethyloxazole-5-carboxylate (122829-61-2) + ethyl 2-chloro-3-oxopentanoate (24045-73-6)

Guidance literature:

Reference yield: 100.0%

ethyl 2-chloro-3-oxopentanoate (24045-73-6) + (4S,5R)-4,5-bis(4-chlorophenyl)-4-methylimidazolidine-2-thione (1033707-10-6) → Ethyl (5R,6S)-5,6-Bis(4-chlorophenyl)-3-ethyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate (1033711-01-1)

Guidance literature:

In ethanol; for 48h; Reflux;

Reference yield: 88.0%

ethyl 2-chloro-3-oxopentanoate (24045-73-6) + aniline (62-53-3) → (E)-2-Chloro-3-phenylamino-pent-2-enoic acid ethyl ester

Guidance literature:

With vanadium(III) chloride; at 20 ℃; for 3h;

Downstream raw materials:

4-Ethyl-5-carbethoxy-imidazol

ethyl 2-amino-4 ethylthiazole-5-carboxylate

ethyl 2-(4-chlorophenoxy)-3-oxopentanoate

5-Ethyl-4-carbethoxyimidazol