5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid

Base Information

Chemical Name:5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid
CAS No.:24106-89-6
Molecular Formula:C15H9ClFNO2
Molecular Weight:289.68900
Hs Code.:2933990090
Mol file:24106-89-6.mol

Synonyms:5-chloro-3-(2-fluoro-phenyl)-1H-indole-2-carboxylic acid;1H-Indole-2-carboxylic acid,5-chloro-3-(2-fluorophenyl);5-Chloro-3-(o-fluorphenyl)indol-2-carbonsaeure;5-Chlor-3-(2-fluorphenyl)indol-2-carbonsaeure;3-(2-Fluorphenyl)-5-chlorindol-2-carbonsaeure;5-chloro-3-(2-fluorophenyl)indole-2-carboxylic acid;

Suppliers and Price of 5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid

Chemical Property:

PSA：53.09000
LogP:4.32560

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid

There total 2 articles about 5-Chloro-3-(2-fluorophenyl)-1H-indole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24106-88-5
ethyl 5-chloro-3-(o-fluorophenyl)indole-2-carboxylate

: 24106-89-6
5-chloro-3-(2-fluoro-phenyl)-indole-2-carboxylic acid

Guidance literature:: ethyl 5-chloro-3-(o-fluorophenyl)indole-2-carboxylate; With methanol; lithium hydroxide; for 4h; Heating / reflux;

With hydrogenchloride; In water;

Reference yield:

: 24106-89-6
5-chloro-3-(2-fluoro-phenyl)-indole-2-carboxylic acid

Guidance literature:: Ester IVa, KOH;

Reference yield:

: 24106-89-6
5-chloro-3-(2-fluoro-phenyl)-indole-2-carboxylic acid

: 36805-97-7
N,N-dimethylformamide di-tert-butyl acetal

: 1130804-87-3
5-chloro-3-(2-fluoro-phenyl)-1H-indole-2-carboxylic acid tert-butyl ester

Guidance literature:: 5-chloro-3-(2-fluoro-phenyl)-indole-2-carboxylic acid; N,N-dimethylformamide di-tert-butyl acetal; In toluene; at 80 ℃; for 3h;

With hydrogenchloride; In water;