2,6-Dibromo-4-methoxyphenol

Base Information

• Chemical Name: 2,6-Dibromo-4-methoxyphenol
• CAS No.: 2423-74-7
• Molecular Formula: C7H6Br2O2
• Molecular Weight: 281.931
• Hs Code.: 2909500000
• DSSTox Substance ID: DTXSID70547674
• Nikkaji Number: J308.053F
• Wikidata: Q82426029
• Mol file: 2423-74-7.mol

Synonyms:2,6-Dibromo-4-methoxyphenol;2423-74-7;2,6-dibromo-4-methoxy-phenol;Phenol, 2,6-dibromo-4-methoxy-;SCHEMBL1119249;AML0050;DTXSID70547674;SGIZMXOUTHAIAN-UHFFFAOYSA-N;MFCD12755175;AKOS030529280;NS-00121;NS00133703;F15247

Chemical Property of 2,6-Dibromo-4-methoxyphenol

Chemical Property:

• PSA: 29.46000
• LogP: 2.92580
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 281.87141
• Heavy Atom Count: 11
• Complexity: 120

Purity/Quality:

95% ^*data from raw suppliers

2,6-Dibromo-4-methoxyphenol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C(C(=C1)Br)O)Br

Technology Process of 2,6-Dibromo-4-methoxyphenol

There total 3 articles about 2,6-Dibromo-4-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-methoxy-phenol (150-76-5) → 1-acetoxy-2,6-dibromo-4-methoxyphenol (2423-74-7)

Guidance literature:

With mono(N,N,N-trimethylbenzenaminium) tribromide; In methanol; dichloromethane; for 12h;

Reference yield:

2,6-dibromohydroquinone (3333-25-3) + dimethyl sulfate (77-78-1) → 1-acetoxy-2,6-dibromo-4-methoxyphenol (2423-74-7)

Guidance literature:

With dimsyl potassium salt;

DOI:10.1021/jo01349a043

Reference yield:

→ 1-acetoxy-2,6-dibromo-4-methoxyphenol (2423-74-7)

Guidance literature:

Quinol, Dimethylsulfat;

DOI:10.1039/j39710000871

upstream raw materials:

4-methoxy-phenol

2,6-dibromohydroquinone

dimethyl sulfate

Downstream raw materials:

2,6-dibromo-4,4-dimethoxy-2,5-cyclohexadien-1-one

3,3'-Dibromo-5,5,5',5'-tetramethoxy-bicyclohexyl-3,6,3',6'-tetraene-2,2'-dione

2-Bromo-6-(2,6-dibromo-4-methoxy-phenoxy)-4,4-dimethoxy-cyclohexa-2,5-dienone

1,3-di(hept-6-ynyl)-2-methoxy-5-methylbenzene

Refernces

• 1、 -. "For a photoelectric conversion element, and a photoelectric conversion element and method for manufacturing the same". Paragraph 0066; 0087-0088. . Retrieved 2020/09/22.
• 2、 Predeus, Alexander V.,Gopalsamuthiram, Vijay,Staples, Richard J.,Wulff, William D.. "Rational synthesis for all All-homocalixarenes". supporting information. p. 911 - 915. Retrieved 2013/02/26.