(2S)-3-Methyl-1,2-butanediol

Base Information

Chemical Name:(2S)-3-Methyl-1,2-butanediol
CAS No.:24347-56-6
Molecular Formula:C5H12O2
Molecular Weight:104.149
Hs Code.:
UNII:ZP64AX90LZ
Nikkaji Number:J63.456E
Wikidata:Q27295833
Mol file:24347-56-6.mol

Synonyms:(2S)-3-Methyl-1,2-butanediol;ZP64AX90LZ;(s)-3-methylbutane-1,2-diol;3-Methyl-1,2-butanediol, (+)-;3-Methyl-1,2-butanediol, (2S)-;3-Methylbutane-1,2-diol, (2S)-;UNII-ZP64AX90LZ;1,2-Butanediol, 3-methyl-, (S)-;1,2-Butanediol, 3-methyl-, (2S)-;1,2-Butanediol, 3-methyl-, (S)-(+)-;24347-56-6;SCHEMBL283630;(S)-3-Methyl-1,2-butanediol;Q27295833

Suppliers and Price of (2S)-3-Methyl-1,2-butanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (2S)-3-Methyl-1,2-butanediol

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:104.083729621
Heavy Atom Count:7
Complexity:43.3

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C(CO)O
Isomeric SMILES:CC(C)[C@@H](CO)O

Technology Process of (2S)-3-Methyl-1,2-butanediol

There total 1 articles about (2S)-3-Methyl-1,2-butanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 636580-98-8
(4S,1'R,2'S)-N-⁽³⁾-(1'-m-chlorobenzoyl-2'-hydroxy-3'-methyl-but-1'-yl)-4-phenyl-5,5-dimethyloxazolidin-2-one

: 24347-56-6
(S)-3-methylbutane-1,2-diol

: 168297-84-5
(4S)-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h;
DOI:10.1016/j.tet.2008.07.012

Reference yield: 99.0%

: 24347-56-6
(S)-3-methylbutane-1,2-diol

: 98-59-9
p-toluenesulfonyl chloride

: 90211-82-8
(2S)-1-tosyloxy-3-methylbutan-2-ol

Guidance literature:: With pyridine; at 25 ℃; for 14h;
DOI:10.1016/00404-0399(50)10116-

Reference yield:

: 24347-56-6
(S)-3-methylbutane-1,2-diol

: 57333-96-7
tacalcitol

Guidance literature:: Multi-step reaction with 11 steps

1: 1H-imidazole; dmap / tetrahydrofuran / 0.25 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 0 - 20 °C

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 12 h / 20 °C

4: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 4 h / 20 °C

5: lithium hexamethyldisilazane / tetrahydrofuran / 15 h / -78 - 20 °C

6: tetrabutyl ammonium fluoride / tetrahydrofuran / 17 h / 65 °C

7: hydrogen; palladium 10% on activated carbon / methanol / 15 h

8: dipyridinium dichromate / dichloromethane / 20 °C

9: n-butyllithium / tetrahydrofuran / 18 h / -78 °C

10: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C / Darkness

11: hydrogen fluoride / acetonitrile; water / 24 h / 20 °C

With 1H-imidazole; dmap; dipyridinium dichromate; n-butyllithium; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; palladium 10% on activated carbon; hydrogen fluoride; tetrabutyl ammonium fluoride; hydrogen; N-ethyl-N,N-diisopropylamine; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1016/j.tetlet.2017.07.103