4-Bromo-2,5-dimethoxyaniline

Base Information

Chemical Name:4-Bromo-2,5-dimethoxyaniline
CAS No.:244236-98-4
Molecular Formula:C8H10BrNO2
Molecular Weight:232.077
Hs Code.:
DSSTox Substance ID:DTXSID90586166
Wikidata:Q82478236
Mol file:244236-98-4.mol

Synonyms:4-bromo-2,5-dimethoxyaniline;244236-98-4;Benzenamine, 4-bromo-2,5-dimethoxy-;SCHEMBL4465544;DTXSID90586166;YLONQFVJDASUEB-UHFFFAOYSA-N;4-bromo-2,5-dimethoxy-phenylamine;STK291038;AKOS003398038;MCULE-3188839814;CS-0248340;EN300-396347;Z1416179328;GXY

Suppliers and Price of 4-Bromo-2,5-dimethoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Bromo-2,5-dimethoxyaniline

Chemical Property:

PSA：44.48000
LogP:2.62970
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:230.98949
Heavy Atom Count:12
Complexity:145

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1N)OC)Br

Technology Process of 4-Bromo-2,5-dimethoxyaniline

There total 5 articles about 4-Bromo-2,5-dimethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 102-56-7,102526-87-4
2,5-dimethoxyaniline

: 244236-98-4
4-bromo-2,5-dimethoxyaniline

Guidance literature:: With bromine; In dichloromethane; at 0 - 20 ℃; regioselective reaction;
DOI:10.1016/j.tetlet.2016.06.091

Reference yield:

: 25245-34-5
1-bromo-2,5-dimethoxybenzene

: 244236-98-4
4-bromo-2,5-dimethoxyaniline

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride; nitric acid / 0 - 20 °C

2: hydrazine hydrate; palladium 10% on activated carbon / methanol / Reflux

With palladium 10% on activated carbon; nitric acid; acetic anhydride; hydrazine hydrate; In methanol;
DOI:10.1039/c5cc02804c