3-propylquinoline

Base Information

• Chemical Name: 3-propylquinoline
• CAS No.: 20668-43-3
• Molecular Formula: C₁₂H₁₃N
• Molecular Weight: 171.242
• Hs Code.: 2933499090
• Mol file: 20668-43-3.mol

Synonyms:3-Propylquinoline;3-n-Propylquinoline

Chemical Property of 3-propylquinoline

Chemical Property:

• Vapor Pressure: 0.00628mmHg at 25°C
• Melting Point: 187 °C
• Boiling Point: 280.9°Cat760mmHg
• PKA: 5.19±0.11(Predicted)
• Flash Point: 115.4°C
• PSA: 12.89000
• Density: 1.03g/cm³
• LogP: 3.18730

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-propylquinoline

There total 5 articles about 3-propylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-bromoquinoline (5332-24-1) + 1-(pyridin-2-yl)butan-1-one (22971-32-0) → 3-propylquinoline (20668-43-3)

Guidance literature:

With 2.9-dimethyl-1,10-phenanthroline; palladium(II) trifluoroacetate; potassium tert-butylate; In toluene; at 120 ℃; for 20h; Inert atmosphere;

DOI:10.1021/acs.orglett.8b02498

Reference yield: 48.0%

2-Aminobenzyl alcohol (5344-90-1) + pentanal (110-62-3) → 3-propylquinoline (20668-43-3)

Guidance literature:

2-Aminobenzyl alcohol; pentanal; With potassium hydroxide; oxygen; copper dichloride; In 1,4-dioxane; at 100 ℃; for 5h; under 760 Torr;

In 1,4-dioxane; at 90 ℃; for 20h;

DOI:10.1016/j.tetlet.2006.07.067

Reference yield:

1,1,1-tri(hydroxymethyl)propane (77-99-6) + aniline (62-53-3) → 3-propylquinoline (20668-43-3)

Guidance literature:

With sulfuric acid; nitrobenzene; at 160 ℃;

DOI:10.1021/ja01201a504

upstream raw materials:

1,1,1-tri(hydroxymethyl)propane

aniline

sulfuric acid

nitrobenzene