2-Oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylic acid diethyl ester

Base Information

• Chemical Name: 2-Oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylic acid diethyl ester
• CAS No.: 24588-62-3
• Molecular Formula: C13H18O5
• Molecular Weight: 254.27900
• Hs Code.: 2932999099
• Mol file: 24588-62-3.mol

Synonyms:Diethyl 2-oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylate;2-oxa-3,3-dicarboethoxybicyclo<2.2.2>oct-5-ene;2-Oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylic acid,diethyl ester;

Chemical Property of 2-Oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylic acid diethyl ester

Chemical Property:

• Boiling Point: 125-130 °C(Press: 1.5 Torr)
• PSA: 61.83000
• Density: 1.188±0.06 g/cm3(Predicted)
• LogP: 1.21640

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylic acid diethyl ester

There total 1 articles about 2-Oxabicyclo[2.2.2]oct-5-ene-3,3-dicarboxylic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-oxa-3,3-dicarboethoxybicyclo<2.2.2>oct-5-ene (24588-62-3)

Guidance literature:

1,3-Cyclohexadien, Mesoxalsaeure-diaethylester, 100-120grad;

Reference yield:

2-oxa-3,3-dicarboethoxybicyclo<2.2.2>oct-5-ene (24588-62-3) → 2,5-dioxa-3-p-toluenesulfonyloxymethyl-tricyclo<4.3.1.0.3,7>decane (83957-54-4)

Guidance literature:

Multi-step reaction with 4 steps

1: LAH / diethyl ether / 3 h / 0 °C

2: 72 percent / N-bromosuccinimide / CHCl₃ / 48 h / Ambient temperature

3: 83 percent / Bu₃SnH, AIBN / diethyl ether / 48 h / Ambient temperature

4: 68 percent / pyridine / benzene / 24 h / Ambient temperature

With pyridine; N-Bromosuccinimide; lithium aluminium tetrahydride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In diethyl ether; chloroform; benzene;

Downstream raw materials:

2,5-dioxa-3-p-toluenesulfonyloxymethyl-tricyclo<4.3.1.0.^3,7>decane