4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2R)-

Base Information

• Chemical Name: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2R)-
• CAS No.: 24604-97-5
• Molecular Formula: C16H14O6
• Molecular Weight: 302.284
• Mol file: 24604-97-5.mol

Synonyms:(R)-4'-methoxy-3',5,7-trihydroxyflavanone;(R)-hesperetin;R-hesperetin;R-HST;

Chemical Property of 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2R)-

Chemical Property:

• PSA: 96.22000
• LogP: 2.51850

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

(R)-Hesperetin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (R)-Hesperetin is a stereoisomer of (S)-Hesperetin (H289480) which is the aglucon of Hesperidin (H281185), a flavanone found in citrus fruits.

Technology Process of 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2R)-

There total 1 articles about 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone (520-33-2,41001-90-5,69097-99-0) → (R)-4'-methoxy-3',5,7-trihydroxyflavanone (24604-97-5,41001-90-5,69097-99-0) + hesperetin (520-33-2,41001-90-5,69097-99-0)

Guidance literature:

With ammonium acetate; In water; isopropyl alcohol; pH=5; Resolution of racemate;

DOI:10.1021/jf1008617

Reference yield:

(R)-4'-methoxy-3',5,7-trihydroxyflavanone (24604-97-5,41001-90-5,69097-99-0) + UDP-glucuronic acid (1245697-26-0,106864-00-0,14520-48-0,30329-32-9,3545-73-1,5918-40-1) → (R)-hesperetin 3-O-glucuronide + (R)-hesperetin 7-O-glucuronide

Guidance literature:

With magnesium chloride; In methanol; dimethyl sulfoxide; at 37 ℃; for 0.0833333h; pH=7.5; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1021/jf1008617

Reference yield:

(R)-4'-methoxy-3',5,7-trihydroxyflavanone (24604-97-5,41001-90-5,69097-99-0) → (R)-hesperetin 7-O-sulfate + (R)-hesperetin 3-O-sulfate

Guidance literature:

With PAPS; magnesium chloride; In dimethyl sulfoxide; at 37 ℃; for 0.0833333h; pH=7.4; Kinetics; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1021/jf1008617

upstream raw materials:

(S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone