(Chloromethyl)p-tolyl sulfoxide

Base Information

• Chemical Name: (Chloromethyl)p-tolyl sulfoxide
• CAS No.: 24824-93-9
• Molecular Formula: C8H9ClOS
• Molecular Weight: 188.678
• DSSTox Substance ID: DTXSID301268042
• Nikkaji Number: J302.964F
• Mol file: 24824-93-9.mol

Synonyms:1-((chloromethyl)sulfinyl)-4-methylbenzene;1-[(Chloromethyl)sulfinyl]-4-methylbenzene;(Chloromethyl)p-tolyl sulfoxide;SCHEMBL2728483;MSHPZDNAAMUIBS-UHFFFAOYSA-N;DTXSID301268042;chloromethyl 4-methylphenyl sulfoxide;1-(chloromethylsulfinyl)-4-methylbenzene;24824-93-9

Chemical Property of (Chloromethyl)p-tolyl sulfoxide

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 188.0062638
• Heavy Atom Count: 11
• Complexity: 141

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)CCl

Technology Process of (Chloromethyl)p-tolyl sulfoxide

There total 7 articles about (Chloromethyl)p-tolyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

chloromethyl p-tolyl sulfide (34125-84-3) → chloromethyl p-tolyl sulfoxide (24824-93-9)

Guidance literature:

With 1-butyl-4-aza-1-azoniabicyclo[2.2.2]octane dichromate; In acetonitrile; for 1.08333h; Heating;

DOI:10.1080/714040957

Reference yield: 90.0%

(S)-methyl p-tolyl sulfoxide (5056-07-5) → chloromethyl p-tolyl sulfoxide (24824-93-9)

Guidance literature:

With sulfuryl dichloride; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4020(01)85289-3

Reference yield: 78.0%

Methyl p-tolyl sulfoxide (934-72-5) → chloromethyl p-tolyl sulfoxide (24824-93-9)

Guidance literature:

With N-chloro-succinimide; silica gel; for 2.5h; Ambient temperature;

DOI:10.1055/s-1986-31793

upstream raw materials:

Methyl p-tolyl sulfoxide

1,2-Dichlor-1-<4-methyl-phenylsulfoxy>-ethylen

4-methylphenyl methylsulfide

(S)-methyl p-tolyl sulfoxide

Downstream raw materials:

1-chloro-4-phenyl-1-(p-tolylsulfinyl)-2-butanol

1-chloro-4-pentenyl p-tolyl sulfoxide

(Z)-1-chloro-1-(p-tolylsulfinyl)-10-nonadecen-2-one

6-[Chloro-(toluene-4-sulfinyl)-methyl]-undecan-6-ol