6-(4-aminophenyl)-2H-pyridazin-3-one

Base Information

Chemical Name:6-(4-aminophenyl)-2H-pyridazin-3-one
CAS No.:24912-35-4
Molecular Formula:C10H9N3O
Molecular Weight:187.201
Hs Code.:
DSSTox Substance ID:DTXSID00446388
Nikkaji Number:J322.297G
Wikidata:Q72440901
ChEMBL ID:CHEMBL49196
Mol file:24912-35-4.mol

Synonyms:24912-35-4;6-(4-aminophenyl)-2H-pyridazin-3-one;6-(4-aminophenyl)pyridazin-3(2{H})-one;3-(4-aminophenyl)-1H-pyridazin-6-one;6-(4-aminophenyl)-2,3-dihydropyridazin-3-one;6-(4-Aminophenyl)pyridazin-3(2(h))-one;3(2H)-Pyridazinone, 6-(4-aminophenyl)-;CHEMBL49196;SCHEMBL1392640;DTXSID00446388;GOAZSGLSVJVOLX-UHFFFAOYSA-N;AKOS005207970;AKOS015941743;3-Hydroxy-6-(4-aminophenyl)pyridazine;6-(4-aminophenyl)-3(2H)-pyridazinone;3(2H)-Pyridazinone,6-(4-aminophenyl)-;EN300-238128;W-202043;F1967-0458

Suppliers and Price of 6-(4-aminophenyl)-2H-pyridazin-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(4-aminophenyl)pyridazin-3(2{H})-one
10mg
$ 45.00

Matrix Scientific
6-(4-Aminophenyl)pyridazin-3(2{H})-one 95%+
1g
$ 611.00

Matrix Scientific
6-(4-Aminophenyl)pyridazin-3(2{H})-one 95%+
5g
$ 2015.00

Matrix Scientific
6-(4-Aminophenyl)pyridazin-3(2{H})-one 95%+
2.500g
$ 1334.00

Biosynth Carbosynth
6-(4-Aminophenyl)pyridazin-3(2{H})-one
10 g
$ 2100.00

Biosynth Carbosynth
6-(4-Aminophenyl)pyridazin-3(2{H})-one
5 g
$ 1181.30

Biosynth Carbosynth
6-(4-Aminophenyl)pyridazin-3(2{H})-one
2 g
$ 525.00

Biosynth Carbosynth
6-(4-Aminophenyl)pyridazin-3(2{H})-one
1 g
$ 315.00

Biosynth Carbosynth
6-(4-Aminophenyl)pyridazin-3(2{H})-one
500 mg
$ 210.00

Total 10 raw suppliers

Chemical Property of 6-(4-aminophenyl)-2H-pyridazin-3-one

Chemical Property:

Melting Point:292-299 °C(Solv: water (7732-18-5))
PKA:11.29±0.40(Predicted)
PSA：72.03000
Density:1.33 g/cm³
LogP:2.01260
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:187.074561919
Heavy Atom Count:14
Complexity:288

Purity/Quality:

97% ^*data from raw suppliers

6-(4-aminophenyl)pyridazin-3(2{H})-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NNC(=O)C=C2)N

Technology Process of 6-(4-aminophenyl)-2H-pyridazin-3-one

There total 4 articles about 6-(4-aminophenyl)-2H-pyridazin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 19064-67-6
6-chloro-2H-pyridazin-3-one

: 214360-73-3
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline

: 24912-35-4
6-(4-aminophenyl)pyridazine-3(2H)-one

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 160 ℃; for 1.5h;

Reference yield:

: 105537-49-3
3-(p-Nitrophenyl)-6-oxo-1,6-dihydropyridazine

: 24912-35-4
6-(4-aminophenyl)pyridazine-3(2H)-one

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethanol; for 6h;
DOI:10.1080/14756366.2019.1651723

Reference yield:

: 100-19-6
(4-nitrophenyl)ethanone

: 24912-35-4
6-(4-aminophenyl)pyridazine-3(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / 88 h / Reflux

1.2: 3 h / Reflux

2.1: palladium on activated charcoal; hydrogen / ethanol / 6 h

With palladium on activated charcoal; hydrogen; acetic acid; In ethanol;
DOI:10.1080/14756366.2019.1651723