(R)-2-Phenylaziridine

Base Information

• Chemical Name: (R)-2-Phenylaziridine
• CAS No.: 25260-42-8
• Molecular Formula: C8H9N
• Molecular Weight: 119.166
• Hs Code.: 2933990090
• European Community (EC) Number: 970-874-4
• Nikkaji Number: J88.335B
• Mol file: 25260-42-8.mol

Synonyms:(S)-2-Phenylaziridine;(R)-2-Phenylaziridine;(2R)-2-PHENYLAZIRIDINE;(2S)-2-PHENYLAZIRIDINE;25260-42-8;18142-08-0;3beta-Phenylaziridine;(S)-2-Phenyl-aziridine;SCHEMBL1688451;MFCD11013242;AKOS006302582;AS-43235;EN300-303726

Chemical Property of (R)-2-Phenylaziridine

Chemical Property:

• PSA: 21.94000
• LogP: 1.65970
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 119.073499291
• Heavy Atom Count: 9
• Complexity: 94.7

Purity/Quality:

(R)-2-Phenylaziridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(N1)C2=CC=CC=C2
• Isomeric SMILES: C1[C@@H](N1)C2=CC=CC=C2

Technology Process of (R)-2-Phenylaziridine

There total 15 articles about (R)-2-Phenylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2S)-2-phenylglycinol (20989-17-7) → (S)-(+)-2-phenylaziridine (25260-42-8)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In toluene; Reflux;

DOI:10.1002/anie.201509731

Reference yield: 85.0%

2R-ammonio-2-phenylethyl sulfate (174261-97-3) → (S)-(+)-2-phenylaziridine (25260-42-8)

Guidance literature:

With sodium hydroxide; In water; toluene; for 18h; Reflux;

DOI:10.1021/jo302615g

Reference yield: 60.0%

(S)-2-azido-2-phenylethanol (126923-25-9) → cis-2-Phenyl-aziridin (25260-42-8)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; Heating;

DOI:10.1039/c39910000095

upstream raw materials:

(S)-2-azido-2-phenylethanol

(R)-2-(methanesulfonyloxy)-2-phenylacetonitrile

methyllithium

(S)-2-Phenyl-1-((S)-toluene-4-sulfinyl)-aziridine

Downstream raw materials:

(S)-5-phenylthiazolidine-2-thione

(4S)-4-phenyl-1,3-thiazolidine-2-thione

C₁₈H₂₅NO

cis-(R)-limonene oxide