5,6,11,12-Tetrahydro-2,9-ethanodibenzo[a,e]cyclooctene

Base Information

Chemical Name:5,6,11,12-Tetrahydro-2,9-ethanodibenzo[a,e]cyclooctene
CAS No.:58002-98-5
Molecular Formula:C₁₈H₁₈
Molecular Weight:234.341
Hs Code.:
Mol file:58002-98-5.mol

Synonyms:[2.2.2](1,2,4)Cyclophane

Suppliers and Price of 5,6,11,12-Tetrahydro-2,9-ethanodibenzo[a,e]cyclooctene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 5,6,11,12-Tetrahydro-2,9-ethanodibenzo[a,e]cyclooctene

Chemical Property:

Vapor Pressure:0.000122mmHg at 25°C
Melting Point:166-168 °C
Boiling Point:345.6°C at 760 mmHg
Flash Point:173.3°C
PSA：0.00000
Density:1.1g/cm³
LogP:3.66900

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5,6,11,12-Tetrahydro-2,9-ethanodibenzo[a,e]cyclooctene

There total 15 articles about 5,6,11,12-Tetrahydro-2,9-ethanodibenzo[a,e]cyclooctene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 43045-00-7
pseudogem-Bis(bromomethyl)<2.2>paracyclophane

: 58002-98-5
1,2,4-<2.2.2>Paracyclophan

Guidance literature:: With zinc; In dimethyl sulfoxide; at 55 ℃; for 4h; sealed tube, vacuum;

Reference yield:

: 43044-98-0,87554-52-7
pseudogem-Bis(hydroxymethyl)<2.2>paracyclophane

: 58002-98-5
1,2,4-<2.2.2>Paracyclophan

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / PBr₃ / CH₂Cl₂ / 0.5 h

2: 73 percent / Zn-powder / dimethylsulfoxide / 4 h / 55 °C / sealed tube, vacuum

With phosphorus tribromide; zinc; In dichloromethane; dimethyl sulfoxide;

Reference yield:

: 1633-22-3
[2.2]Paracyclophan

: 58002-98-5
1,2,4-<2.2.2>Paracyclophan

Guidance literature:: Multi-step reaction with 7 steps

1: 74 percent / Aluminum chloride / CH₂Cl₂ / 0.25 h / -50 - -20 °C

2: 55 percent / Hydrochloric acid / 3.75 h / 55 °C

3: KOH, Bromine / dioxane / 17 h / Ambient temperature

4: 72 percent / Lithium aluminum hydride / tetrahydrofuran / 96 h / Heating

5: Acetic anhydride, p-toluenesulfonic acid / acetic acid / Heating

6: Boron trifluoride-etherate / benzene / 0.5 h / Ambient temperature

7: 1.) tosylhydrazine, sulfuric acid; 2.) sodium methoxide / 1.) Benzene, reflux, 15 min; 2.) THF, irradiation, 20 deg C, 70 min.

With hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; sulfuric acid; boron trifluoride diethyl etherate; bromine; sodium methylate; acetic anhydride; toluene-4-sulfonic acid; toluene-4-sulfonic acid hydrazide; In tetrahydrofuran; 1,4-dioxane; dichloromethane; acetic acid; benzene;
DOI:10.1021/jo01308a005