4-(MethoxyMethoxy)benzoicacid

Base Information

• Chemical Name: 4-(MethoxyMethoxy)benzoicacid
• CAS No.: 25458-44-0
• Molecular Formula: C9H10O4
• Molecular Weight: 182.176
• Hs Code.: 2918999090
• Mol file: 25458-44-0.mol

Synonyms:4-methoxymethyleneoxybenzoic acid;p-Methoxy-methoxybenzoesaeure;Benzoic acid,4-(methoxymethoxy);4-methoxymethoxybenzoic acid;4-Methoxymethoxybenzoesaeure;p-methoxymethyloxybenzoic acid;

Chemical Property of 4-(MethoxyMethoxy)benzoicacid

Chemical Property:

• PSA: 55.76000
• LogP: 1.36750
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

4-(Methoxymethoxy)benzoicAcid ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(MethoxyMethoxy)benzoicacid

There total 14 articles about 4-(MethoxyMethoxy)benzoicacid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

chloromethyl methyl ether (107-30-2) + 4-hydroxy-benzoic acid (99-96-7) → 4-(methoxymethoxy)benzoic acid (25458-44-0)

Guidance literature:

chloromethyl methyl ether; 4-hydroxy-benzoic acid; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 17h;

With potassium hydroxide; In methanol; at 20 ℃; for 3h;

With hydrogenchloride; In water;

Reference yield: 97.0%

4-(methoxymethoxy)benzoic acid methoxymethyl ester → 4-(methoxymethoxy)benzoic acid (25458-44-0)

Guidance literature:

With water; potassium hydroxide; In methanol; at 20 ℃; for 5h;

Reference yield: 93.5%

ethyl 4-(methoxymethoxy)benzoate (5942-30-3) → 4-(methoxymethoxy)benzoic acid (25458-44-0)

Guidance literature:

With potassium hydroxide; In ethanol; for 16h; Ambient temperature;

DOI:10.1016/S0957-4166(00)80176-7

upstream raw materials:

ethyl 4-(methoxymethoxy)benzoate

n-butyl 4-(methoxymethoxy)benzoate

4-hydroxy-benzoic acid

4-hydroxybenzoic acid, butyl ester

Downstream raw materials:

C₂₃H₂₀O₇

N-(6-bromo-2-pyridyl)-4-(methoxymethoxy)benzamide

phenyl 4-(methoxymethoxy)benzoate

4-(methoxymethoxy)benzoyl chloride

Refernces

• 1、 Müllerová, Monika,Maciel, Dina,Nunes, Nádia,Wrobel, Dominika,Stofik, Marcel,?ervenková ?tastná, Lucie,Krupková, Alena,Cu?ínová, Petra,Nováková, Kate?ina,Bo?ík, Matěj,Maly, Marek,Maly, Jan,Rodrigues, Jo?o,Stra?ák, Tomá?. "Carbosilane Glycodendrimers for Anticancer Drug Delivery: Synthetic Route, Characterization, and Biological Effect of Glycodendrimer-Doxorubicin Complexes". . p. 276 - 290. Retrieved 2022/01/04.
• 2、 -. "S1P1 AGONIST AND APPLICATION THEREOF". . . Retrieved 2021/10/02.