2-(3-Mercaptopropyl)pentanedioic acid

Base Information

Chemical Name:2-(3-Mercaptopropyl)pentanedioic acid
CAS No.:254737-29-6
Deprecated CAS:359715-56-3
Molecular Formula:C8H14O4S
Molecular Weight:
Hs Code.:
UNII:TV8F3S5KLG
Nikkaji Number:J1.938.636H
Pharos Ligand ID:S7KFH7QX9U2V
ChEMBL ID:CHEMBL303352
Mol file:254737-29-6.mol

Synonyms:2-(3-mercaptopropyl)pentanedioic acid;2-MPPA cpd;GPI 5693

Suppliers and Price of 2-(3-Mercaptopropyl)pentanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(3-Mercaptopropyl)pentanedioic acid

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:206.06128010
Heavy Atom Count:13
Complexity:181

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(CCC(=O)O)C(=O)O)CS

Technology Process of 2-(3-Mercaptopropyl)pentanedioic acid

There total 7 articles about 2-(3-Mercaptopropyl)pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 254737-43-4
6-[(triphenylmethyl)thio]-1,3-hexanedicarboxylic acid

: 254737-29-6
2-(3-mercaptopropyl)pentanedioic acid

Guidance literature:: With trisopropylsilane; trifluoroacetic acid; In dichloromethane; for 0.5h;
DOI:10.1021/jm020515w

Reference yield:

: 848952-59-0
(R)-3-(2-oxo-tetrahydro-thiopyran-3-yl)propionic acid

: 254737-29-6
2-(3-mercaptopropyl)pentanedioic acid

Guidance literature:: With hydrogenchloride; at 100 ℃;
DOI:10.1021/jm049258g

Reference yield:

: 254737-40-1
2,2-dimethyl-5-[3-[(triphenylmethyl)thio]propyl]-[1,3]dioxane-4,6-dione

: 254737-29-6
2-(3-mercaptopropyl)pentanedioic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 81 percent / NaOAc / 2-methyl-propan-2-ol / 60 °C

2: 1.75 N aq. NaOH / 3 h / 100 °C

3: 4.30 g / dimethylsulfoxide / 3 h / 130 °C

4: 75 percent / TFA; trisopropylsilane / CH₂Cl₂ / 0.5 h

With sodium hydroxide; trisopropylsilane; sodium acetate; trifluoroacetic acid; In dichloromethane; dimethyl sulfoxide; tert-butyl alcohol; 1: Michael addition;
DOI:10.1021/jm020515w