3-(4-Bromophenyl)cyclobutanone

Base Information

Chemical Name:3-(4-Bromophenyl)cyclobutanone
CAS No.:254892-91-6
Molecular Formula:C10H9BrO
Molecular Weight:225.085
Hs Code.:2914700090
European Community (EC) Number:822-589-0
DSSTox Substance ID:DTXSID40404624
Wikidata:Q82208900
Mol file:254892-91-6.mol

Synonyms:3-(4-Bromophenyl)cyclobutanone;254892-91-6;3-(4-bromophenyl)cyclobutan-1-one;Cyclobutanone, 3-(4-bromophenyl)-;3-(4-bromo-phenyl)-cyclobutanone;MFCD04038979;3-(4-BROMOPHENYL)-CYCLOBUTANE-1-ONE;SCHEMBL5612;DTXSID40404624;FOQRHYVNXUDNKL-UHFFFAOYSA-N;AKOS004115284;PB24838;AS-32459;SY017720;CS-0053973;FT-0719235;EN300-43632;A853975;F8889-7086;Z385459408

Suppliers and Price of 3-(4-Bromophenyl)cyclobutanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Synthonix
Cyclobutanone,3-(4-bromophenyl)- 95+%
10g
$ 1680.00

Synthonix
Cyclobutanone,3-(4-bromophenyl)- 95+%
1g
$ 340.00

SynQuest Laboratories
3-(4-Bromophenyl)cyclobutan-1-one
1 g
$ 952.00

Matrix Scientific
Cyclobutanone
1g
$ 594.00

Labseeker
3-(4-bromophenyl)cyclobutanone 95
100g
$ 2933.00

Labseeker
3-(4-bromophenyl)cyclobutanone 95
25g
$ 1467.00

J&W Pharmlab
3-(4-Bromo-phenyl)-cyclobutanone 97%
5g
$ 1390.00

J&W Pharmlab
3-(4-Bromo-phenyl)-cyclobutanone 97%
1g
$ 398.00

Crysdot
3-(4-Bromophenyl)cyclobutanone 95+%
5g
$ 523.00

Chemenu
3-(4-Bromophenyl)cyclobutanone 95%
5g
$ 489.00

Total 15 raw suppliers

Chemical Property of 3-(4-Bromophenyl)cyclobutanone

Chemical Property:

PSA：17.07000
LogP:2.89560
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:223.98368
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99%, ^*data from raw suppliers

Cyclobutanone,3-(4-bromophenyl)- 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC1=O)C2=CC=C(C=C2)Br
Uses 3-(4-Bromophenyl)cyclobutanone is used in the preparations of selective T-type calcium channel blockers.

Technology Process of 3-(4-Bromophenyl)cyclobutanone

There total 6 articles about 3-(4-Bromophenyl)cyclobutanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.2%

: 254892-87-0
3-(4-bromophenyl)-2,2-dichlorocyclobutan-1-one

: 254892-91-6
3-(4-bromophenyl)cyclobutanone

Guidance literature:: With acetic acid; zinc; at 20 ℃; for 4h; Reflux;

Reference yield: 56.0%

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 127-19-5,116057-81-9
N,N-dimethyl acetamide

: 254892-91-6
3-(4-bromophenyl)cyclobutanone

Guidance literature:: N,N-dimethyl acetamide; With trifluoromethylsulfonic anhydride; In 1,2-dichloro-ethane; at 5 ℃; for 0.5h;

1-bromo-4-ethenyl-benzene; With 2,4,6-trimethyl-pyridine; In 1,2-dichloro-ethane; for 18h; Reflux;
DOI:10.1021/acs.orglett.8b03121

Reference yield: 25.42%

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 107-06-2,52399-93-6
1,2-dichloro-ethane

: 254892-91-6
3-(4-bromophenyl)cyclobutanone

Guidance literature:: 1,2-dichloro-ethane; With trifluoromethylsulfonic anhydride; In N,N-dimethyl acetamide; at -15 ℃; for 0.5h; Large scale;

1-bromo-4-ethenyl-benzene; With 2,4,6-trimethyl-pyridine; In N,N-dimethyl acetamide; 1,2-dichloro-ethane; at 90 ℃; for 16h; Large scale;