2-(4-CHLORO-PHENYL)-2-OXO-ETHYL-AMMONIUM BROMIDE

Base Information

• Chemical Name: 2-(4-CHLORO-PHENYL)-2-OXO-ETHYL-AMMONIUM BROMIDE
• CAS No.: 256331-92-7
• Molecular Formula: BrH*C₈H₈ClNO
• Molecular Weight: 250.523
• Hs Code.: 2922399090
• Mol file: 256331-92-7.mol

Synonyms:

Chemical Property of 2-(4-CHLORO-PHENYL)-2-OXO-ETHYL-AMMONIUM BROMIDE

Chemical Property:

• PSA: 43.09000
• LogP: 3.13980

Purity/Quality:

2-(4-CHLORO-PHENYL)-2-OXO-ETHYL-AMMONIUM BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-CHLORO-PHENYL)-2-OXO-ETHYL-AMMONIUM BROMIDE

There total 2 articles about 2-(4-CHLORO-PHENYL)-2-OXO-ETHYL-AMMONIUM BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chlorobenzoylmethyl bromide (536-38-9) → [2-(4'-chlorophenyl)-2-oxoethyl]ammonium bromide (256331-92-7)

Guidance literature:

Multi-step reaction with 2 steps

1: CHCl₃ / 12 h / 20 °C

2: 0.608 g / aq. HBr / methanol / 120 h / 20 °C

With hydrogen bromide; In methanol; chloroform; 1: Delepine reaction;

DOI:10.1055/s-2006-942390

Reference yield:

(4-chloro-phenacyl)-hexamethylenetetraminium; bromide → [2-(4'-chlorophenyl)-2-oxoethyl]ammonium bromide (256331-92-7)

Guidance literature:

With hydrogen bromide; In methanol; at 20 ℃; for 120h;

DOI:10.1055/s-2006-942390

Reference yield:

[2-(4'-chlorophenyl)-2-oxoethyl]ammonium bromide (256331-92-7) → C12H14ClN2O(1+)*CH3O4S(1-)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / acetonitrile / Heating

2: 84 percent / acetonitrile / 2 h / Heating

In acetonitrile; 1: Condensation / 2: Methylation;

DOI:10.1002/(SICI)1522-2675(19991110)82:11<1981::AID-HLCA1981>3.0.CO;2-T

upstream raw materials:

4-chlorobenzoylmethyl bromide

Refernces