(R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID

Base Information

Chemical Name:(R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID
CAS No.:25654-51-7
Molecular Formula:C12H13NO4
Molecular Weight:235.24
Hs Code.:
Mol file:25654-51-7.mol

Synonyms:(R)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylic acid;Benzyloxycarbonyl-D-2-azetidincarbonsaeure;(2R)-N-benzyloxycarbonylazetidine-2-carboxylic acid;(2R)-1-phenylmethoxycarbonylazetidine-2-carboxylic acid;(R)-1-Cbz-azetidine-2-carboxylic acid;(2R,2S)-1-benzyloxycarbonylazetidine-2-carboxylic acid;(R)-N-Cbz-azetidine-2-carboxylic acid;(2R)-1-Cbz-2-azetidine-carboxylic acid;1-[(Benzyloxy)Carbonyl]-2-Azetidinecarboxylic Acid;

Suppliers and Price of (R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylicacid 95+%
1g
$ 455.00

Chemenu
(R)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylicacid 95%
1g
$ 430.00

American Custom Chemicals Corporation
(R)-1-((BENZYLOXY)CARBONYL)AZETIDINE-2-CARBOXYLIC ACID 95.00%
1G
$ 975.45

American Custom Chemicals Corporation
(R)-1-((BENZYLOXY)CARBONYL)AZETIDINE-2-CARBOXYLIC ACID 95.00%
5MG
$ 499.72

Alichem
(R)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylicacid
1g
$ 386.88

Acrotein
(2R)-1-Cbz-2-azetidine-carboxylicacid 97%
0.25g
$ 254.83

Acrotein
(2R)-1-Cbz-2-azetidine-carboxylicacid 97%
0.5g
$ 407.92

ACHEMBLOCK
(2R)-1-Cbz-2-azetidine-carboxylicacid 95%
250MG
$ 310.00

Total 18 raw suppliers

Chemical Property of (R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID

Chemical Property:

Boiling Point:421.2±45.0 °C(Predicted)
PKA:3.99±0.20(Predicted)
PSA：66.84000
Density:1.362±0.06 g/cm3(Predicted)
LogP:1.42000
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(R)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID

There total 4 articles about (R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 7729-30-8,20063-89-2
(R)-azetidine-2-carboxylic acid

: 25654-51-7
(2R,2S)-1-benzyloxycarbonylazetidine-2-carboxylic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; sodium chloride; In toluene;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 25654-51-7
(2R,2S)-1-benzyloxycarbonylazetidine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / H₂O

With sodium hydroxide; In water;
DOI:10.1016/S0957-4166(00)82184-9