Phenol, 4-methoxy-2-(3-methyl-2-butenyl)-

Base Information

• Chemical Name: Phenol, 4-methoxy-2-(3-methyl-2-butenyl)-
• CAS No.: 25974-58-7
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• ChEMBL ID: CHEMBL508246
• DSSTox Substance ID: DTXSID50473745
• Nikkaji Number: J597.960I
• Wikidata: Q82303351
• Mol file: 25974-58-7.mol

Synonyms:25974-58-7;Phenol, 4-methoxy-2-(3-methyl-2-butenyl)-;CHEMBL508246;SCHEMBL24804415;DTXSID50473745

Chemical Property of Phenol, 4-methoxy-2-(3-methyl-2-butenyl)-

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 192.115029749
• Heavy Atom Count: 14
• Complexity: 195

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=CCC1=C(C=CC(=C1)OC)O)C

Technology Process of Phenol, 4-methoxy-2-(3-methyl-2-butenyl)-

There total 18 articles about Phenol, 4-methoxy-2-(3-methyl-2-butenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-methoxy-phenol (150-76-5) + prenyl bromide (870-63-3) → 4-methoxy-2-(3-methylbut-2-enyl)phenol (25974-58-7)

Guidance literature:

With sodium; In diethyl ether; Heating;

DOI:10.1021/ol0499699

Reference yield: 75.0%

2-methyl-3-buten-2-ol (115-18-4) + 4-methoxy-phenol (150-76-5) → 4-methoxy-2-(3-methylbut-2-enyl)phenol (25974-58-7)

Guidance literature:

With mesoporous silica containing bimetallic Cu-Al (CuAl-KIT-5); In 1,2-dichloro-ethane; at 60 ℃; for 16h;

DOI:10.1002/cctc.201200332

Reference yield: 60.0%

4-methoxyphenyl 3-methylbut-2-enyl carbonate (1200591-29-2) → 4-methoxy-2-(3-methylbut-2-enyl)phenol (25974-58-7)

Guidance literature:

With triphenylphosphine; tetrabutylammonium tricarbonylnitrosylferrate; In toluene; at 110 ℃; regioselective reaction;

DOI:10.1021/ol902291z

upstream raw materials:

1-methoxy-4-((2-methylbut-3-en-2-yl)oxy)benzene

4-methoxy-phenol

prenyl bromide

2-methyl-3-buten-2-ol

Downstream raw materials:

2,2-dimethyl-2H-chromene

6-methoxy-2,2-dimethyl-2H-chromene

8,8'-Bis(6-methoxy-2,2-dimethylchromene)

4-Methoxy-2-[4-methoxy-2-(3-methyl-but-2-enyl)-phenoxy]-6-(3-methyl-but-2-enyl)-phenol