4-Oxazoleethanol, 2-[(1E)-2-phenylethenyl]-

Base Information

Chemical Name:4-Oxazoleethanol, 2-[(1E)-2-phenylethenyl]-
CAS No.:259809-69-3
Molecular Formula:C13H13NO2
Molecular Weight:215.252
Hs Code.:
Mol file:259809-69-3.mol

Synonyms:4-(2-hydroxyethyl)-2-(trans-β-styryl)oxazole;4-(2-hydroxyethyl)-2-(trans-styryl)oxazole;2-{2-[(E)-2-phenylethenyl]oxazol-4-yl}-1-ethanol;2-[2-((E)-Styryl)-oxazol-4-yl]-ethanol;

Suppliers and Price of 4-Oxazoleethanol, 2-[(1E)-2-phenylethenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Oxazoleethanol, 2-[(1E)-2-phenylethenyl]-

Chemical Property:

PSA：46.26000
LogP:2.37980

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Oxazoleethanol, 2-[(1E)-2-phenylethenyl]-

There total 3 articles about 4-Oxazoleethanol, 2-[(1E)-2-phenylethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 259809-68-2
2-[(E)-2-Phenylethenyl]-4-vinyloxazole

: 259809-69-3
2-{2-[(E)-2-Phenylethenyl]oxazol-4-yl}-1-ethanol

Guidance literature:: 2-[(E)-2-Phenylethenyl]-4-vinyloxazole; With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; at 20 ℃; for 15h;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; at 20 ℃; for 6h;
DOI:10.1016/j.bmc.2005.09.056

Reference yield:

: 259809-68-2
2-[(E)-2-Phenylethenyl]-4-vinyloxazole

: 280-64-8
9-bora-bicyclo[3.3.1]nonane

: 259809-69-3
2-{2-[(E)-2-Phenylethenyl]oxazol-4-yl}-1-ethanol

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; ethyl acetate;

Reference yield:

: 259809-67-1
2-[(E)-2-phenylethenyl]oxazole-4-carbaldehyde

: 259809-69-3
2-{2-[(E)-2-Phenylethenyl]oxazol-4-yl}-1-ethanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.5 h / 20 °C

1.2: 79 percent / tetrahydrofuran; hexane / 2 h / 20 °C

2.1: 9-borabicyclo[3.3.1]nonane / tetrahydrofuran / 15 h / 20 °C

2.2: 99 percent / NaOH; H₂O₂ / tetrahydrofuran; H₂O / 6 h / 20 °C

With n-butyllithium; 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; hexane; 1.2: Wittig reaction;
DOI:10.1016/j.bmc.2005.09.056