Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)-

Base Information

Chemical Name:Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)-
CAS No.:64107-71-7
Molecular Formula:C₁₀H₁₄N₂S*ClH
Molecular Weight:230.761
Hs Code.:
DSSTox Substance ID:DTXSID10214318

Synonyms:Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)-;trans-3-Methyl-4a,5,6,7,8,8a-hexahydrothiazolo(3,2-a)benzimidazole hydrochloride;64107-71-7;DTXSID10214318;LS-151973

Suppliers and Price of Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)-

Chemical Property:

Vapor Pressure:0.000769mmHg at 25°C
Boiling Point:306.5°C at 760 mmHg
Flash Point:139.2°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:230.0644474
Heavy Atom Count:14
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CSC2=NC3CCCCC3N12.Cl
Isomeric SMILES:CC1=CSC2=N[C@@H]3CCCC[C@H]3N12.Cl

Technology Process of Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)-

There total 4 articles about Thiazolo(3,2-a)benzimidazole, 4a,5,6,7,8,8a-hexahydro-3-methyl-, hydrochloride, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 30086-64-7,64107-70-6,139121-99-6,139237-77-7
trans-2-thiohexahydrobenzimidazole

: 78-95-5
chloroacetone

: 64107-71-7,64107-98-8
(4aR,8aR)-3-Methyl-4a,5,6,7,8,8a-hexahydro-benzo[4,5]imidazo[2,1-b]thiazole; hydrochloride

Guidance literature:: In ethanol; for 18h; Heating;
DOI:10.1021/jm00137a022

Reference yield:

: 1436-59-5
cis-cyclohexane-1,2-diamine

: 64107-71-7,64107-98-8
(4aR,8aS)-3-Methyl-4a,5,6,7,8,8a-hexahydro-benzo[4,5]imidazo[2,1-b]thiazole; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: concd. HCl / ethanol; H₂O / 18 h / Heating

2: ethanol / 18 h / Heating

With hydrogenchloride; In ethanol; water;
DOI:10.1021/jm00137a022

Reference yield:

: 1121-22-8,1436-59-5,20439-47-8,21436-03-3,41013-43-8,694-83-7
trans-1,2-Diaminocyclohexane

: 64107-71-7,64107-98-8
(4aR,8aR)-3-Methyl-4a,5,6,7,8,8a-hexahydro-benzo[4,5]imidazo[2,1-b]thiazole; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / concd. HCl / ethanol; H₂O / 18 h / Heating

2: 89 percent / ethanol / 18 h / Heating

With hydrogenchloride; In ethanol; water;
DOI:10.1021/jm00137a022