1-[(4-Hydroxybenzoyl)amino]-3-phenylthiourea

Base Information

Chemical Name:1-[(4-Hydroxybenzoyl)amino]-3-phenylthiourea
CAS No.:26036-25-9
Molecular Formula:C14H13N3O2S
Molecular Weight:287.342
Hs Code.:
DSSTox Substance ID:DTXSID301331073
Nikkaji Number:J830.265K
ChEMBL ID:CHEMBL1403152
Mol file:26036-25-9.mol

Synonyms:26036-25-9;1-(4-HYDROXYBENZOYL)-4-PHENYL-3-THIOSEMICARBAZIDE;1-[(4-hydroxybenzoyl)amino]-3-phenylthiourea;2-(4-Hydroxybenzoyl)-N-phenylhydrazine-1-carbothioamide;MLS000714014;CHEMBL1403152;SCHEMBL19478515;DTXSID301331073;HMS2765J18;MFCD00245863;STK864440;AKOS000579685;MS-10775;SMR000273494;CS-0358727;2-(4-hydroxybenzoyl)N-phenylhydrazinecarbothiamide;4-hydroxy-N-[(phenylcarbamothioyl)amino]benzamide;SR-01000325944;SR-01000325944-1;2-[(4-hydroxyphenyl)carbonyl]-N-phenylhydrazinecarbothioamide

Suppliers and Price of 1-[(4-Hydroxybenzoyl)amino]-3-phenylthiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[(4-Hydroxybenzoyl)amino]-3-phenylthiourea

Chemical Property:

PSA：105.48000
LogP:2.87840
XLogP3:2.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:287.07284784
Heavy Atom Count:20
Complexity:337

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=S)NNC(=O)C2=CC=C(C=C2)O

Technology Process of 1-[(4-Hydroxybenzoyl)amino]-3-phenylthiourea

There total 4 articles about 1-[(4-Hydroxybenzoyl)amino]-3-phenylthiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 103-72-0
phenyl isothiocyanate

: 5351-23-5
4-hydroxybenzoic acid hydrazide

: 26036-25-9
2-(4-hydroxybenzoyl)-N-phenylhydrazincarbothioamide

Guidance literature:: In ethanol; for 12h; Reflux;
DOI:10.5012/jkcs.2010.54.01.077

Reference yield: 71.0%

: 26036-25-9
2-(4-hydroxybenzoyl)-N-phenylhydrazincarbothioamide

Guidance literature:: With (1S)-10-camphorsulfonic acid; In methanol; at 55 ℃; for 6h; Inert atmosphere;

Reference yield:

: 120-47-8
Ethyl 4-hydroxybenzoate

: 26036-25-9
2-(4-hydroxybenzoyl)-N-phenylhydrazincarbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol; water / Reflux

2: ethanol / 2 h

With hydrazine hydrate; In ethanol; water;
DOI:10.1016/j.molstruc.2021.131547