N(alpha)-Benzyloxycarbonylphenylalanylchloromethane

Base Information

Chemical Name:N(alpha)-Benzyloxycarbonylphenylalanylchloromethane
CAS No.:26049-98-9
Molecular Formula:C18H18 Cl N O3
Molecular Weight:331.799
Hs Code.:2924299090
European Community (EC) Number:803-619-1
NSC Number:189673,157082,251810
ChEMBL ID:CHEMBL1977116

Synonyms:26049-98-9;N(alpha)-Benzyloxycarbonylphenylalanylchloromethane;benzyl N-(4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate;Z-L-Phe-CMK;NSC-251810;N(.alpha.)-Benzyloxycarbonylphenylalanylchloromethane;N-(Benzyloxycarbonyl)-L-phenylalanine chloromethyl ketone;N-[(Benzyloxy)carbonyl]-L-phenylalanine chloromethyl ketone;L-[.alpha.-(Chloroacetyl)phenethyl]carbamic acid, benzyl ester;SCHEMBL6439753;CHEMBL1977116;Carbamic acid, benzyl ester, L-;HMS3373P11;NSC157082;NSC189673;NSC251810;AKOS024386644;AB89497;NSC-157082;NSC-189673;Carbamic acid, phenylmethyl ester, (S)-;NCI60_001135;FT-0603934;A818153;N-(4-chloro-3-oxo-1-phenylbutan-2-yl)carbamic acid (phenylmethyl) ester;(phenylmethyl) N-(4-chloranyl-3-oxidanylidene-1-phenyl-butan-2-yl)carbamate

Suppliers and Price of N(alpha)-Benzyloxycarbonylphenylalanylchloromethane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Z-L-phenylalanine-chloromethylketone
500mg
$ 355.00

Total 6 raw suppliers

Chemical Property of N(alpha)-Benzyloxycarbonylphenylalanylchloromethane

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:2.99E-10mmHg at 25°C
Melting Point:107-108oC(lit.)
Boiling Point:503.1oC at 760 mmHg
PKA:10.74±0.46(Predicted)
Flash Point:258.1oC
PSA：55.40000
Density:1.228g/cm3
LogP:3.72290
Storage Temp.:-20°C
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:331.0975211
Heavy Atom Count:23
Complexity:377

Purity/Quality:

95% ^*data from raw suppliers

Z-L-phenylalanine-chloromethylketone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 34
Safety Statements: 26-27-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)CCl)NC(=O)OCC2=CC=CC=C2

Technology Process of N(alpha)-Benzyloxycarbonylphenylalanylchloromethane

There total 2 articles about N(alpha)-Benzyloxycarbonylphenylalanylchloromethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: dimethylsulfoxonium 2-oxo-3-(benzyloxycarbonylamino)-4-phenylbutylide

: 26049-98-9
(S)-[3-Chloro-2-oxo-1-(phenylmethyl)propyl]carbamic acid,phenylmethyl ester

Guidance literature:: With methanesulfonic acid; lithium chloride; In tetrahydrofuran; at 0 - 70 ℃; for 2h;

Reference yield:

: 26049-98-9
(S)-[3-Chloro-2-oxo-1-(phenylmethyl)propyl]carbamic acid,phenylmethyl ester

Guidance literature:

Reference yield:

: 26049-98-9
(S)-[3-Chloro-2-oxo-1-(phenylmethyl)propyl]carbamic acid,phenylmethyl ester

: 540-63-6
ethane-1,2-dithiol

: 289031-38-5
[1-(5,6-dihydro-[1,4]dithiin-2-yl)-2-phenyl-ethyl]-carbamic acid benzyl ester

Guidance literature:: (S)-[3-Chloro-2-oxo-1-(phenylmethyl)propyl]carbamic acid,phenylmethyl ester; ethane-1,2-dithiol; With boron trifluoride diethyl etherate; In tetrahydrofuran; at 20 ℃;

With pyridine; at 100 ℃; for 2h;
DOI:10.1016/S0968-0896(00)00062-6