2-hydroxymuconic acid

Base Information

• Chemical Name: 2-hydroxymuconic acid
• CAS No.: 3685-55-0
• Molecular Formula: C6H6 O5
• Molecular Weight: 158.111
• Mol file: 3685-55-0.mol

Synonyms:2-Hydroxymuconicacid

Chemical Property of 2-hydroxymuconic acid

Chemical Property:

• Vapor Pressure: 2.77E-05mmHg at 25°C
• Boiling Point: 332.6°Cat760mmHg
• Flash Point: 169.2°C
• PSA: 94.83000
• Density: 1.559g/cm³
• LogP: 0.15370

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-hydroxymuconic acid

There total 1 articles about 2-hydroxymuconic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxymuconic 6-semialdehyde (783334-77-0) → 2-hydroxymuconic acid (3685-55-0)

Guidance literature:

With 2-hydroxymuconic 6-semialdehyde dehydrogenase; NAD; In various solvent(s); at 24 ℃; for 1h; pH=7.5;

DOI:10.1271/bbb.60264

Reference yield:

2-hydroxymuconic acid (3685-55-0) → 4-oxalocrotonic acid

Guidance literature:

With 4-oxalocrotonate tautomerase; In various solvent(s); at 24 ℃; pH=7.0;

DOI:10.1271/bbb.60264

Reference yield:

2-hydroxymuconic acid (3685-55-0) → 4-hydroxy-2-oxopentanoic acid (41453-55-8,3318-73-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 4-oxalocrotonate tautomerase / various solvent(s) / 24 °C / pH 7.0

2: MgSO₄; 4-oxalocrotonate decarboxylase / various solvent(s) / 1 h / 24 °C / pH 8.0

3: MgSO₄; 2-oxopent-4-enoate hydratase / 0.5 h / 24 °C

With 2-oxopent-4-enoate hydratase; 4-oxalocrotonate decarboxylase; 4-oxalocrotonate tautomerase; magnesium sulfate; In various solvent(s);

DOI:10.1271/bbb.60264

upstream raw materials:

2-hydroxymuconic 6-semialdehyde

Downstream raw materials:

4-hydroxy-2-oxopentanoic acid

2-oxopent-4-enoic acid

Refernces