(2R)-flavanone

Base Information

Chemical Name:(2R)-flavanone
CAS No.:27439-12-9
Molecular Formula:C₁₅H₁₂O₂
Molecular Weight:224.259
Hs Code.:
UNII:86J2CJ48SY
Nikkaji Number:J86.473K
Wikidata:Q27116702
Metabolomics Workbench ID:55278
Mol file:27439-12-9.mol

Synonyms:(2R)-flavanone;(+)-Flavanone;27439-12-9;(R)-2-phenylchroman-4-one;Flavanone, (+)-;Flavanone, (R)-(+)-;(R)-2-Phenyl-4-chromanone;(2R)-2-phenyl-2,3-dihydro-4H-chromen-4-one;(2R)-2-phenyl-2,3-dihydrochromen-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-2-phenyl-, (2R)-;86J2CJ48SY;(2R)-2,3-Dihydro-2-phenyl-4H-benzopyran-4-one;(+)-(R)-2,3-dihydro-2-phenyl-4H-1-benzopyran;(2R)-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one;UNII-86J2CJ48SY;(R)-flavanone;SCHEMBL12660199;CHEBI:36105;ZONYXWQDUYMKFB-OAHLLOKOSA-N;A827595;Q27116702

Suppliers and Price of (2R)-flavanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one
50mg
$ 550.00

TRC
(R)-2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one
25mg
$ 290.00

Total 5 raw suppliers

Chemical Property of (2R)-flavanone

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:224.083729621
Heavy Atom Count:17
Complexity:281

Purity/Quality:

99% ^*data from raw suppliers

(R)-2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(OC2=CC=CC=C2C1=O)C3=CC=CC=C3
Isomeric SMILES:C1[C@@H](OC2=CC=CC=C2C1=O)C3=CC=CC=C3
Uses (R)-2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one (Propafenone Impurity H (EP/BP/USP)) is an impurity of Propafenone (P757500), a sodium channel blocker and an antiarrhythmic (class IC) compound.

Technology Process of (2R)-flavanone

There total 160 articles about (2R)-flavanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 525-82-6,66585-04-4
FLAVONE

: 487-26-3,17002-31-2,24271-98-5,27439-12-9
(2S)-flavanone

: 487-26-3,17002-31-2,24271-98-5,27439-12-9
(R)-flavanone

Guidance literature:: FLAVONE; With Dimethylphenylsilane; C₅₀H₅₂N₂; bis(pentafluorophenyl)borohydride; In toluene; at 20 ℃; for 1h; Inert atmosphere; Glovebox;

With trifluoroacetic acid; In toluene; at 20 ℃; for 0.166667h; enantioselective reaction; Inert atmosphere; Glovebox;
DOI:10.1055/s-0036-1588474

Reference yield: 99.0%

: 525-82-6,66585-04-4
FLAVONE

: 487-26-3,17002-31-2,24271-98-5,27439-12-9
(2S)-flavanone

: 487-26-3,17002-31-2,24271-98-5,27439-12-9
(R)-flavanone

Guidance literature:: FLAVONE; With Dimethylphenylsilane; C₅₀H₅₂N₂; bis(pentafluorophenyl)borohydride; In toluene; at 20 ℃; for 1h; Inert atmosphere; Glovebox;

With trifluoroacetic acid; In toluene; at 20 ℃; for 0.166667h; enantioselective reaction; Inert atmosphere; Glovebox;
DOI:10.1055/s-0036-1588474

Reference yield: 93.0%

: 491-38-3
1-benzopyran-4(4H)-one

: 98-80-6
phenylboronic acid

: 1277188-71-2
C₂₁H₁₈O₂

: 487-26-3,17002-31-2,24271-98-5,27439-12-9
(2S)-flavanone

Guidance literature:: With [Rh(OH)(cod)]2; (S)-MeO-F₁₂-BIPHEP; In water; toluene; at 20 ℃; for 1h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol2004148