2-METHOXYPHENYLPHOSPHINE

Base Information

• Chemical Name: 2-METHOXYPHENYLPHOSPHINE
• CAS No.: 126590-38-3
• Molecular Formula: C₇H₉OP
• Molecular Weight: 140.122
• Mol file: 126590-38-3.mol

Synonyms:2-Methoxyphenylphosphine

Chemical Property of 2-METHOXYPHENYLPHOSPHINE

Chemical Property:

• Vapor Pressure: 0.13mmHg at 25°C
• Boiling Point: 225.4°Cat760mmHg
• Flash Point: 90.1°C
• PSA: 22.82000
• Density: g/cm³
• LogP: 1.19560

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

2-METHOXY PHOSPHINO BENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHOXYPHENYLPHOSPHINE

There total 1 articles about 2-METHOXYPHENYLPHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl [2-(methoxy)phenyl]phosphonate (15286-17-6) → (2-methoxyphenyl)phosphine (126590-38-3)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 1h;

DOI:10.1021/jo800969x

Reference yield:

(2-methoxyphenyl)phosphine (126590-38-3) + (4S,7S)-4,7-dimethyl-1,3,2-dioxathiepane 2,2-dioxide (220224-82-8) → (2R,5R)-1-(2-methoxyphenyl)-2,5-dimethylphospholane (1043508-40-2)

Guidance literature:

(2-methoxyphenyl)phosphine; With potassium tert-butylate; In tetrahydrofuran; at -30 - 0 ℃; for 1h;

(4S,7S)-4,7-dimethyl-1,3,2-dioxathiepane 2,2-dioxide; In tetrahydrofuran; at 20 ℃; for 2h;

With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 48h; Further stages.;

DOI:10.1021/jo800969x

Reference yield:

(2-methoxyphenyl)phosphine (126590-38-3) + (R,R)-2,6-dimethylheptane-3,5-diol cyclic sulfate → (S,S)-1-(o-anisyl)-2,4-diisopropylphosphetane

Guidance literature:

(2-methoxyphenyl)phosphine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

(R,R)-2,6-dimethylheptane-3,5-diol cyclic sulfate; In tetrahydrofuran; at 20 ℃; for 0.333333h;

With sec.-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1055/s-2001-18064

upstream raw materials:

diethyl [2-(methoxy)phenyl]phosphonate

Downstream raw materials:

(2R,5R)-1-(2-methoxyphenyl)-2,5-dimethylphospholane