1-(DiMethylaMino)-2-propanol N-Oxide

Base Information

• Chemical Name: 1-(DiMethylaMino)-2-propanol N-Oxide
• CAS No.: 27607-29-0
• Molecular Formula: C₅H₁₃NO₂
• Molecular Weight: 119.164
• Mol file: 27607-29-0.mol

Synonyms:N-(2-Hydroxypropyl)-N,N-dimethylamin-N-oxid;Dimepranol N-Oxide;N,N-dimethylaminoisopropanol N-oxide;

Chemical Property of 1-(DiMethylaMino)-2-propanol N-Oxide

Chemical Property:

• Melting Point: 171-172 °C (decomp)
• PKA: 13.70±0.20(Predicted)
• PSA: 49.66000
• LogP: -0.03770

Purity/Quality:

99% ^*data from raw suppliers

Dimepranol N-Oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Dimepranol N-Oxide is a metabolite of Dimepranol (D460402).

Technology Process of 1-(DiMethylaMino)-2-propanol N-Oxide

There total 1 articles about 1-(DiMethylaMino)-2-propanol N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

1-methyl-2-N,N-dimethylaminoethanol (108-16-7,53657-16-2) → N-(2-hydroxypropyl)-N,N-dimethylamine N-oxide (27607-29-0)

Guidance literature:

With dihydrogen peroxide;

DOI:10.1016/0022-328X(84)80698-1

Reference yield: 59.0%

DPB025 (37763-62-5) + N-(2-hydroxypropyl)-N,N-dimethylamine N-oxide (27607-29-0) → 4,4,6-trimethyl-2,2-bis(4-methoxyphenyl)-1,3-dioxa-4-azonia-2-boratacyclohexane (95890-43-0)

Guidance literature:

In ethanol; a mixt. of EtOH soln. of amine oxide and 1 equiv of borane in EtOH was refluxed for 15 min; cooled, resulting crystals (soln. was concd. if necessary) were sepd., recrystd. from EtOH-petroleum ether; elem. anal.;

DOI:10.1016/0022-328X(84)80698-1

upstream raw materials:

1-methyl-2-N,N-dimethylaminoethanol

Downstream raw materials:

4,4,6-trimethyl-2,2-bis(4-methoxyphenyl)-1,3-dioxa-4-azonia-2-boratacyclohexane

Refernces

• 1、 Kliegel, Wolfgang,Ahlenstiel, Eckart. "SYNTHESE UND THERMISCH INDUZIERTE UMLAGERUNG DER DIARYLBORCHELATE VON N-(2-HYDROXYALKYL)-N,N-DIALKYLAMIN-N-OXIDEN". . p. 173 - 188. Retrieved 2007/10/02.