4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine

Base Information

Chemical Name:4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine
CAS No.:284665-40-3
Molecular Formula:C11H6F6N2S
Molecular Weight:312.238
Hs Code.:2934100090
European Community (EC) Number:672-127-5
DSSTox Substance ID:DTXSID80369384
Wikidata:Q82156442
Mol file:284665-40-3.mol

Synonyms:284665-40-3;4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine;2-amino-4-(3,5-bis(trifluoromethyl)phenyl)thiazole;4-[3,5-bis(trifluoromethyl)phenyl]-1,3-thiazol-2-amine;4-(3,5-bis-trifluoromethylphenyl)thiazol-2-ylamine;2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiazole;SCHEMBL3278201;DTXSID80369384;MFCD00124615;AKOS010956678;SB82666;MS-11007;FT-0740105;4-(3,5-Bistrifluoromethylphenyl)thiazol-2-ylamine;A819463;4-(3,5-bis-trifluoromethylphenyl)thiazol-2-ylamine, AldrichCPR

Suppliers and Price of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3,5-bis(Trifluoromethyl)phenyl)thiazol-2-amine
50mg
$ 60.00

Matrix Scientific
4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine 95+%
1g
$ 341.00

Matrix Scientific
4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine 95+%
5g
$ 874.00

Crysdot
4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine 95+%
25g
$ 452.00

Chemenu
4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine 95%
25g
$ 426.00

American Custom Chemicals Corporation
4-(3,5-BIS-TRIFLUOROMETHYLPHENYL)THIAZOL-2-YLAMINE 95.00%
5MG
$ 504.35

Alichem
4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine
25g
$ 501.60

AK Scientific
2-Amino-4-(3,5-bis(trifluoromethyl)phenyl)thiazole
10g
$ 424.00

AK Scientific
2-Amino-4-(3,5-bis(trifluoromethyl)phenyl)thiazole
1g
$ 131.00

AHH
4-(3,5-Bis-trifluoromethylphenyl)thiazol-2-ylamine 98%
1g
$ 260.00

Total 17 raw suppliers

Chemical Property of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine

Chemical Property:

Melting Point:146.3-147.6 °C
Boiling Point:338.793 °C at 760 mmHg
Flash Point:158.697 °C
PSA：67.15000
Density:1.51 g/cm³
LogP:5.01110
Storage Temp.:2-8°C
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:1
Exact Mass:312.01558835
Heavy Atom Count:20
Complexity:323

Purity/Quality:

97% ^*data from raw suppliers

4-(3,5-bis(Trifluoromethyl)phenyl)thiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=CSC(=N2)N

Technology Process of 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine

There total 2 articles about 4-(3,5-Bis(trifluoromethyl)phenyl)thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.3%

: 30071-93-3
3,5-bis(trifluoromethyl)phenyl methyl ketone

: 17356-08-0
thiourea

: 284665-40-3
4-[3,5-bis(trifluoromethyl)phenyl]-1,3-thiazole-2-amine

Guidance literature:: 3,5-bis(trifluoromethyl)phenyl methyl ketone; With phenyltrimethylammonium tribromide; In tetrahydrofuran; at 20 ℃; for 5h;

thiourea; With sodium sulfate; In ethanol; for 0.5h; Heating / reflux;

Reference yield: 83.3%

: 17356-08-0
thiourea

: 284665-40-3
4-[3,5-bis(trifluoromethyl)phenyl]-1,3-thiazole-2-amine

Guidance literature:: 3,5-bis(trifluoromethyl)phenyl methyl ketone; With phenyltrimethylammonium tribromide; In tetrahydrofuran; at 20 ℃; for 5h;

thiourea; With sodium sulfate; In ethanol; for 0.5h; Heating / reflux;