2,6-Diazabicyclo[3.2.1]octane-2-carboxylic acid 1,1-dimethylethyl ester

Base Information

Chemical Name:2,6-Diazabicyclo[3.2.1]octane-2-carboxylic acid 1,1-dimethylethyl ester
CAS No.:286946-98-3
Molecular Formula:C11H20N2O2
Molecular Weight:212.28900
Hs Code.:
Mol file:286946-98-3.mol

Synonyms:tert-butyl 2.6-diazabicyclo[3.2.1]octane-2-carboxylate;

Suppliers and Price of 2,6-Diazabicyclo[3.2.1]octane-2-carboxylic acid 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate
5g
$ 2250.00

Matrix Scientific
tert-Butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate
1g
$ 900.00

J&W Pharmlab
2,6-Diaza-bicyclo[3.2.1]octane-2-carboxylicacidtert-butylester 96%
500mg
$ 490.00

Total 7 raw suppliers

Chemical Property of 2,6-Diazabicyclo[3.2.1]octane-2-carboxylic acid 1,1-dimethylethyl ester

Chemical Property:

Boiling Point:295.4±13.0 °C(Predicted)
PKA:10.65±0.20(Predicted)
PSA：41.57000
Density:1.076±0.06 g/cm3(Predicted)
LogP:1.62440

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,6-Diazabicyclo[3.2.1]octane-2-carboxylic acid 1,1-dimethylethyl ester

There total 6 articles about 2,6-Diazabicyclo[3.2.1]octane-2-carboxylic acid 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₆N₂O₄

: 286946-98-3
tert-butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 6h; under 760.051 Torr;
DOI:10.1021/jm070018l

Reference yield:

: 286946-90-5
benzyl 5-(hydroxyimino)-2-azabicyclo[2.2.1]heptane-2-carboxylate

: 286946-98-3
tert-butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1.08 g / trimethylsilylpolyphosphate / CH₂Cl₂ / 12 h / 20 °C

2.1: BH₃*SMe₂ / tetrahydrofuran / 14 h / 20 °C

2.2: 60 percent / n-propylamine / toluene / 3 h / 60 °C

3.1: triethylamine / CH₂Cl₂ / 2 h / 20 °C

4.1: H₂ / Pd/C / methanol / 6 h / 760.05 Torr

With trimethylsilylpolyphosphate; dimethylsulfide borane complex; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; 1.1: Beckman rearrangement;
DOI:10.1021/jm070018l

Reference yield:

: 286946-66-5
benzyl 3-oxo-2,6-diazabicyclo[3.2.1]-octane-6-carboxylate

: 286946-98-3
tert-butyl 2,6-diazabicyclo[3.2.1]octane-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: BH₃*SMe₂ / tetrahydrofuran / 14 h / 20 °C

1.2: 60 percent / n-propylamine / toluene / 3 h / 60 °C

2.1: triethylamine / CH₂Cl₂ / 2 h / 20 °C

3.1: H₂ / Pd/C / methanol / 6 h / 760.05 Torr

With dimethylsulfide borane complex; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm070018l