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Pronetalol hydrochloride

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Name

Pronetalol hydrochloride

EINECS N/A
CAS No. 51-02-5 Density 1.074g/cm3
PSA 32.26000 LogP 4.06410
Solubility N/A Melting Point 184°
Formula C15H19 N O . Cl H Boiling Point 322.4°Cat760mmHg
Molecular Weight 265.81 Flash Point 84.3°C
Transport Information N/A Appearance N/A
Safety A poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and HCl. Risk Codes N/A
Molecular Structure Molecular Structure of 51-02-5 (2-ISOPROPYLAMINO-1-(2-NAPHTHYL)ETHANOL HYDROCHLORIDE) Hazard Symbols N/A
Synonyms

2-Naphthalenemethanol,a-[(isopropylamino)methyl]-,hydrochloride (8CI);2-Naphthalenemethanol, a-[[(1-methylethyl)amino]methyl]-, hydrochloride (9CI);2-Isopropylamino-1-(2-naphthyl)ethanol hydrochloride;AY 6204;DL-Pronethalolhydrochloride;ICI 38174;Nethalide hydrochloride;Pronetalol hydrochloride;Pronethalol hydrochloride;dl-Pronethalol hydrochloride;

 

Pronetalol hydrochloride Chemical Properties

Molecular Formula of Pronetalol hydrochloride (CAS NO.51-02-5): C15H20ClNO
Molecular Weight: 265.7784 g/mol
Structure of Pronetalol hydrochloride (CAS NO.51-02-5):
                      
IUPAC Name: 1-Naphthalen-2-yl-2-(propan-2-ylamino)ethanol hydrochloride
Canonical SMILES: CC(C)NCC(C1=CC2=CC=CC=C2C=C1)O.Cl
InChI: InChI=1S/C15H19NO.ClH/c1-11(2)16-10-15(17)14-8-7-12-5-3-4-6-13(12)9-14;/h3-9,11,15-17H,10H2,1-2H3;1H
InChIKey: QONLGXRPRAIDGI-UHFFFAOYSA-N

Pronetalol hydrochloride Toxicity Data With Reference

1.    

orl-mus LD50:512 mg/kg

    BJPCAL    British Journal of Pharmacology and Chemotherapy. 25 (1965),577.
2.    

ipr-mus LD50:145 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 195 (1972),57.
3.    

ivn-mus LD50:45 mg/kg

    BJPCAL    British Journal of Pharmacology and Chemotherapy. 25 (1965),577.

Pronetalol hydrochloride Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 13 , 1977,p. 227.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Pronetalol hydrochloride Safety Profile

A poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition Pronetalol hydrochloride (CAS NO.51-02-5) emits very toxic fumes of NOx and HCl.

Pronetalol hydrochloride Specification

 Pronetalol hydrochloride , its cas register number is 51-02-5. It also can be called 2-Naphthalenemethanol, alpha-(((1-methylethyl)amino)methyl)-, hydrochloride ; 2-Isopropylamino-1-(2-naphthyl)ethanol hydrochloride ; and Naphthalenemethanol, alpha-((isopropylamino)methyl)-, hydrochloride .

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