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Prostaglandin F2a tris salt

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Name

Prostaglandin F2a tris salt

EINECS 254-002-3
CAS No. 38562-01-5 Density N/A
PSA 184.70000 LogP 1.40400
Solubility H2O: 1 mg/mL Melting Point 25-35oC
Formula C20H34O5.C4H11NO3 Boiling Point 531 °C at 760 mmHg
Molecular Weight 475.623 Flash Point 289 °C
Transport Information N/A Appearance N/A
Safety 53-45 Risk Codes 60-22
Molecular Structure Molecular Structure of 38562-01-5 (Prostaglandin F2a tris salt) Hazard Symbols ToxicT
Synonyms

2-amino-2-(hydroxymethyl)propane-1,3-diol; (E)-7-[(1R,2S,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid;Panacelan F tromethamine salt;Enzaprost F compd. with trisamine;Dinoprost tromethamine (JAN/USP);Prostaglandin F2.alpha., compd. with 2-amino-2-hydroxymethyl-1,3-propanediol (1:1);Dinoprost tromethamine;7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic acid, tromethamine salt;Prosta-5,13-dien-1-oic acid, (5Z,9.alpha.,11.alpha.,13E,15S)-9,11,15-trihydroxy- compd. with (trimethylolamino)methane;Prosta-5,13-dien-1-oic acid, 9,11, 15-trihydroxy-, (5Z,9.alpha.,11.alpha.,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1);Ensaprost;Pronalgon F;Prosta-5,13-dien-1-oic acid,9,11,15-trihydroxy-,(5Z,9R,11R,13E,- 15S)-,compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1);Zinoprost;Dinoprost Trometamol;

Article Data 11

Prostaglandin F2a tris salt Specification

The Prostaglandin F2a tris salt, with the CAS registry number 38562-01-5, is also known as Panacelan F tromethamine salt. Its EINECS registry number is 254-002-3. This chemical's molecular formula is C24H45NO8 and molecular weight is 475.62. Its IUPAC name is called 2-amino-2-(hydroxymethyl)propane-1,3-diol; 7-[3,5-dihydroxy-2-(3-hydroxyoct-1-enyl)cyclopentyl]hept-5-enoic acid. The product should be sealed at temperature of -18 °C. This chemical's classification code ares Abortifacient Agents; Abortifacient agents, nonsteroidal; Human Data; Oxytocic; Oxytocics; Prostaglandin; Reproductive Control Agents; Reproductive Effect.

Physical properties of Prostaglandin F2a tris salt: (1)ACD/LogP: 2.14; (2)ACD/LogD (pH 5.5): 1.33; (3)ACD/LogD (pH 7.4): -0.47; (4)ACD/BCF (pH 5.5): 3.86; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 53.76; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 5; (9)#H bond donors: 4; (10)#Freely Rotating Bonds: 15; (11)Flash Point: 289 °C; (12)Enthalpy of Vaporization: 92.76 kJ/mol; (13)Boiling Point: 531 °C at 760 mmHg; (14)Vapour Pressure: 1.71E-13 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemicals that at low levels can cause damage to health. It is harmful if swallowed. Besides, it may impair fertility. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible). What's more, it must be avoid exposure - obtain special instructions before use.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O.C(C(CO)(CO)N)O
(2)InChI: InChI=1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2
(3)InChIKey: IYGXEHDCSOYNKY-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 111mg/kg (111mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 21, Pg. 623, 1974.
mouse LD50 intraperitoneal 101mg/kg (101mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 21, Pg. 623, 1974.
mouse LD50 intravenous 331mg/kg (331mg/kg)   Drugs in Japan Vol. 6, Pg. 327, 1982.
mouse LD50 oral 711mg/kg (711mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 21, Pg. 623, 1974.
mouse LD50 subcutaneous 214mg/kg (214mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 21, Pg. 623, 1974.
rat LD50 intramuscular 59mg/kg (59mg/kg)   Drugs in Japan Vol. 6, Pg. 327, 1982.
rat LD50 intraperitoneal 101mg/kg (101mg/kg)   Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 517, 1975.
rat LD50 intravenous 101mg/kg (101mg/kg)   Drugs in Japan Vol. 6, Pg. 327, 1982.
rat LD50 oral 665mg/kg (665mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Yakkyoku. Pharmacy. Vol. 32, Pg. 1129, 1981.
rat LD50 subcutaneous 66mg/kg (66mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 21, Pg. 623, 1974.

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