Product Name: Rapamycin
Synonyms: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0~4,9~]hexatriaconta-16,24,26,28-tetraen-2,3,10,14,20-penton(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0~4,9~]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone ;(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-méthoxycyclohexyl]-1-méthyléthyl}-19,30-diméthoxy-15,17,21,23,29,35-hexaméthyl-11,36-dioxa-4-azatricyclo[30.3.1.0~4,9~]hexatriaconta-16,24,26,28-tétraène-2,3,10,14,20-pentone
Product Categories: Active Pharmaceutical Ingredients;Immunosuppressant;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling
Molecular Structure of Sirolimus (CAS NO.53123-88-9) :
Molecular Formula of Sirolimus (CAS NO.53123-88-9) : C₅₁H₇₉NO₁₃
Molecular Weight of Sirolimus (CAS NO.53123-88-9) : 914.18
CAS NO: 53123-88-9
Index of Refraction: 1.55
Surface Tension: 51.4 dyne/cm
Density: 1.18 g/cm³
Flash Point: 542.3 °C
Enthalpy of Vaporization: 160.72 kJ/mol
Boiling Point: 973 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Melting point: 183-185°C
Storage temp: -20°C
Sensitive: Moisture Sensitive/Light Sensitive/Hygroscopic

Sirolimus was originally developed as an antifungal agent. However, this was abandoned when it was discovered that it had potent immunosuppressive and antiproliferative properties. It has since been shown to prolong the life of mice and might also be useful in the treatment of certain cancers.

 Sirolimus (CAS NO.53123-88-9) is also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as "Rapa Nui", hence the name. It is marketed under the trade name Rapamune by Wyeth.

Hazard CodesXi
Risk Statements 36/38
R36/38:Irritating to eyes and skin.
Safety Statements 22-24/25-37/39-26
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S37/39:Wear suitable gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.