- Sodium
- Sodium 2,4-dimethylbenzenesulfonate
- SODIUM γ-FLUORO-β-HYDROXYBUTYRATE
- Sodium ((3-methoxy-1-methyl-3-oxo-1-propenyl)amino)phenylacetate
- Sodium (+)-10-camphorsulfonate
- Sodium (2-carbamoylphenoxy)acetate
- Sodium (2-methyl-4-chlorophenoxy)acetate
- Sodium (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
- Sodium (C10-16)alkylbenzenesulfonate
- Sodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)propyl)-1,3-benzodioxole-2,2-
- 30034-13-04-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-, (4-methoxyphenyl)methylester, 4-oxide, (2S,4S,5R,6R)- (9CI)
- 300-34-5L-Tyrosine, 3-amino-
- 300345-76-0(1S,2S)-N-Methylsulfonyl-1,2-diphenylethanediamine, 98+%
- 300353-13-3Benzeneacetamide, α-(cyclopentylmethyl)-4-(methylsulfonyl)-N-2-thiazolyl-, (αR)-
- 300353-42-8Benzeneacetamide,3,4-dichloro-a-(cyclopentylmethyl)-N-2-pyridinyl-
- 3003-84-7Furan,2-(chloromethyl)tetrahydro-
- 300386-87-23-oxo-7α,12α-diformyloxy-5β-cholan-24-oic acid
- 300-38-9L-Tyrosine,3,5-dibromo-
- 300-39-03,5-Diiodo-L-tyrosine dehydrate
- 30041-95-3Acetic acid,2-(4-cyanophenoxy)-, ethyl ester
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Sodium cefamandole |
EINECS | 250-009-0 |
| CAS No. | 30034-03-8 | Density | N/A |
| PSA | 203.97000 | LogP | -1.23150 |
| Solubility | N/A | Melting Point |
>175 °C (dec.) |
| Formula | C18H17N6NaO5S2 | Boiling Point | N/A |
| Molecular Weight | 484.492 | Flash Point | N/A |
| Transport Information | N/A | Appearance | White solid |
| Safety | 26-36 | Risk Codes | 36/37/38-42/43 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[(hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-mandelamido-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodiumsalt, D- (8CI);Cefamandole sodium;Cefamandole sodium salt;Kefdole;Sodium7-D-mandelamido-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylate;Sodium [6R-[6a,7b(R*)]]-7-[(hydroxyphenylacetyl)amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; |
Article Data | 2 |
Sodium cefamandole Chemical Properties
Chemistry informtion about Cefamandole Sodium (CAS NO.30034-03-8) is:
IUPAC Name: Sodium (6r,7r)-7-[[(2r)-2-Hydroxy-2-Phenylacetyl]Amino]-3-[(1-Methyltetrazol-5-Yl)Sulfanylmethyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
Synonyms: Cefamandole Sodium ; Cefamandole Sodium Salt ; Sodium [6r-[6alpha,7beta(R*)]]-7-[[(Formyloxy)Phenylacetyl]Amino]-3-[[(1-Methyl-1h-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate ; Sodium (6r-(6alpha,7beta(R*)))-7-((Hydroxyphenylacetyl)Amino)-3-(((1-Methyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylate ; Sodium Cefamandole ; 5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylicacid,7-Mandelamido-3-(((1-Met ; Monosodiumsalt,D-Hyl-1h-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo ; 5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 7-[(Hydroxyphenylacetyl)Amino]-3-[[(1-Methyl-1h-Tetrazol-5-Yl)Thio]Methyl]-8-Oxo-, Monosodium Salt, [6r-[6α,7β(R*)]]-
MF: C18H17N6NaO5S2
MW: 484.48
EINECS: 250-009-0
Melting Point: >175°C (dec.)
Storage temp.: Store at RT.
Following is the molecular structure of Cefamandole Sodium (CAS NO.30034-03-8) is:
Sodium cefamandole Uses
Cefamandole Sodium (CAS NO.30034-03-8) can be used as broad-spectrum semi-synthetic cephalosporin antibiotic.
Sodium cefamandole Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 4460mg/kg (4460mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984. | |
| mouse | LD50 | oral | > 19900mg/kg (19900mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984. | |
| mouse | LD50 | subcutaneous | 10300mg/kg (10300mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984. | |
| rabbit | LD | intravenous | > 2gm/kg (2000mg/kg) | behavioral: food intake (animal) kidney, ureter, and bladder: "changes in tubules (including acute renal failure, acute tubular necrosis)" kidney, ureter, and bladder: other changes in urine composition | Chemotherapy Vol. 27(Suppl, |
| rat | LD50 | intravenous | 4410mg/kg (4410mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984. | |
| rat | LD50 | oral | > 16600mg/kg (16600mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984. | |
| rat | LD50 | subcutaneous | 12100mg/kg (12100mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 115, 1984. |
Sodium cefamandole Safety Profile
Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
Hazard Codes:
Xn
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 2
RTECS: XI0389000
Sodium cefamandole Specification
Cefamandole Sodium (CAS NO.30034-03-8) is white solid.
What can I do for you?
Get Best Price
