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THYMOXAMINE HYDROCHLORIDE

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Name

THYMOXAMINE HYDROCHLORIDE

EINECS N/A
CAS No. 964-52-3 Density 1.018g/cm3
PSA 38.77000 LogP 3.78610
Solubility N/A Melting Point 208-210°
Formula C16H25 N O3 . Cl H Boiling Point 371°Cat760mmHg
Molecular Weight 315.84 Flash Point 178.2°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Experimental reproductive effects. Used as an adrenergic blocker. When heated to decomposition it emits toxic fumes of NOx and HCl. Risk Codes 20/21/22
Molecular Structure Molecular Structure of 964-52-3 (MOXISYLYTE HYDROCHLORIDE) Hazard Symbols
Synonyms

Carvacrol,5-[2-(dimethylamino)ethoxy]-, acetate (ester), hydrochloride (8CI); Carvacrol,5-[2-(dimethylamino)ethoxy]-, acetate, hydrochloride (6CI,7CI); Phenol,4-[2-(dimethylamino)ethoxy]-2-methyl-5-(1-methylethyl)-, acetate (ester),hydrochloride (9CI); 4-(2-Dimethylaminoethoxy)-5-isopropyl-2-methylphenyl acetatehydrochloride; Arlitine; Carlytene; M 101; M 101 (vasodilator); Moxisylytehydrochloride; Moxyl; Opilon; Opilon hydrochloride; Thymoxamine hydrochloride;Uroalpha; Vasoklin

 

THYMOXAMINE HYDROCHLORIDE Chemical Properties

The molecular formula of THYMOXAMINE HYDROCHLORIDE (964-52-3) is C16H26ClNO3 and its formula weight is 315.84 g/mol.Its EINECS is 213-519-4. The density of THYMOXAMINE HYDROCHLORIDE (964-52-3) is 1.018g/cm3 and it has a melting point of 208–210°C.The boiling point is 371°C at 760mmHg.Polarizability is 10-24cm3.Enthalpy of vaporization is 61.8 kJ/mol.Its flash point is 178.2°C and the vapor pressure is 1.06E-05 mmHg at 25°C .The chemical synonyms of THYMOXAMINE HYDROCHLORIDE (964-52-3) are (2-(4-acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylaminehydrochloride;5-(2-(n,n-dimethylamino)ethoxy)carvacrolacetatehydrochloride;arlitene;carlytene;carvacrol,5-(2-(n,n-dimethylamino)ethoxy)-,acetate,hydrochloride;chlorhydratedeacetoxy-thymoxy-ethyl-dimethylamine;m-101 and opilonhydrochloride .The molecular structure of THYMOXAMINE HYDROCHLORIDE (964-52-3) is .

THYMOXAMINE HYDROCHLORIDE Toxicity Data With Reference

1.   

orl-rat LD50:740 mg/kg

   THERAP    Therapie. 26 (1971),775.
2.   

ipr-rat LD50:96 mg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
3.   

scu-rat LD50:190 mg/kg

   THERAP    Therapie. 26 (1971),775.
4.   

ivn-rat LD50:32 mg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
5.   

orl-mus LD50:255 mg/kg

   JPPMAB    Journal of Pharmacy and Pharmacology. 32 (1980),209.
6.   

ipr-mus LD50:81 mg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
7.   

scu-mus LD50:152 mg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
8.   

ivn-mus LD50:28 mg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
9.   

orl-dog LDLo:700 mg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
10.   

ivn-dog LD50:54,500 µg/kg

   KSRNAM    Kiso to Rinsho. Clinical Report. 16 (1982),1147.
11.   

orl-mky LDLo:1500 mg/kg

THYMOXAMINE HYDROCHLORIDE Safety Profile

Poison by ingestion, subcutaneous, intravenous and intraperitoneal routes. Experimental reproductive effects. Used as an adrenergic blocker. When heated to decomposition it emits toxic fumes of NOx and HCl. Hazard symbols is Xn.
Risk statements is 20/21/22.
Safety statements is 36.

THYMOXAMINE HYDROCHLORIDE Specification

Its extinguishing agent is foam, carbon dioxide , sand and dry powder.
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