The Nobel Prize in Chemistry 1948 was awarded to Arne Tiselius "for his research on electrophoresis and adsorption analysis, especially for his discoveries concerning the complex nature of the serum proteins".
 

Globulin is one of the three types of serum proteins, the others being albumin and fibrinogen. Some globulins are produced in the liver, while others are made by the immune system. Albumin is also a globular protein, but not a globulin. Electrophoresis is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field. This electrokinetic phenomenon was observed for the first time in 1807 by Reuss, who noticed that the application of a constant electric field caused clay particles dispersed in water to migrate. It is ultimately caused by the presence of a charged interface between the particle surface and the surrounding fluid.