Paul Berg (born on June 30, 1926 in Brooklyn, New York, U.S.) is an American biochemist and professor emeritus at Stanford University.

He graduated from Abraham Lincoln High School in 1943, received his B.S. in biochemistry from Penn State University in 1948 and Ph.D. in biochemistry from Case Western Reserve University in 1952. In 1980 he shared half of the Nobel Prize for Chemistry with the team of Walter Gilbert and Frederick Sanger.
Paul Berg's doctorate paper is now known as the conversion of formic acid, formaldehyde and methanol to fully reduced states of methyl groups in methionine.
Berg was also awarded the National Medal of Science in 1983, by Ronald Reagan.
Berg is Professor Emeritus at Stanford and ceased conducting research in 2000.